Results 271 to 280 of about 3,191,200 (316)

Genetic hemochromatosis and HLA linkage

Human Genetics, 1987
We previously reported five families with primary, genetic (idiopathic) hemochromatosis in whom HLA typing of subjects indicated that a homozygous-heterozygous mating had almost certainly occurred and in whom inheritance of the disease trait was best explained by an autosomal recessive mode of inheritance.
Powell, Lawrie W., Ferluga, Janez, Halliday, June W., Bassett, Mark L., Kohonen-Corish, Maija, Serjeantson, Sue   +5 more
openaire   +4 more sources

Linkage and Association to Genetic Markers

2015
Genetic markers that are sufficiently polymorphic (as measured by their heterozygosities) can be used in linkage and association analyses to detect Mendelian segregation underlying disease phenotypes. Each type of analysis can either be based on a specific genetic model or not make any assumptions about the mode of inheritance of the disease ...
openaire   +3 more sources

Genetic Linkage in Soybean

Crop Science, 2002
Mapping mutants of classical linkage groups 6 and 8 (CLGs 6 and 8) in soybean [Glycine max (L.) Merr.] can enhance the identification of important agronomic traits. Genetic data suggest that CLGs 6 and 8 may belong to the same linkage group. Our objectives were to determine if CLGs 6 and 8 are the same or different linkage groups and to determine the ...
A. Assibi Mahama, Reid G. Palmer, K. S. Lewers   +2 more
openaire   +2 more sources

The Use of Linkage in Genetic Counselling

Human Heredity, 1970
Methods are outlined for incorporating information from genetical linkage in the prediction of genotypes, for discrimination of genetic entities, for advice to adults, and for antenatal diagnosis ...
openaire   +3 more sources

MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations.

Genomics, 1987
E. Lander, E. Lander, P. Green, Jeff Abrahamson, A. Barlow, M. Daly, S. Lincoln, Lee Newburg   +7 more
semanticscholar   +1 more source

Introduction to Genetic Linkage Analysis

Cancer Investigation, 1997
Advances in molecular methodology have resulted in the successful genetic mapping and isolation of the genes responsible for numerous simple Mendelian disorders such as cystic fibrosis, neurofibromatosis, and Huntington disease. Recently, researchers have begun to successfully study diseases with more complex inheritance, such as breast cancer.
openaire   +3 more sources

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

Nature Genetics, 1995
E. Lander, L. Kruglyak
semanticscholar   +1 more source

SNP Discovery by GBS in Olive and the Construction of a High-Density Genetic Linkage Map

Biochemical Genetics, 2016
A. Ipek, Kübra Yılmaz, Pelin Sıkıcı, N. A. Tangu, A. Öz, M. Bayraktar, M. Ipek, H. Gülen   +7 more
semanticscholar   +1 more source

Genetic Linkage in Neurologic Diseases

New England Journal of Medicine, 1987
Until recently, the hope of identifying genes associated with dominant inherited neurologic disorders seemed remote. Now that has changed. The powerful techniques of molecular biology have provided methods for locating, by linkage analysis, the genes responsible for several of these diseases and for using the same techniques for presymptomatic or ...
openaire   +3 more sources

The 1993–94 Généthon human genetic linkage map

Nature Genetics, 1994
G. Gyapay, J. Morissette, A. Vignal, C. Dib, C. Fizames, P. Millasseau, Sophie Marc, G. Bernardi, M. Lathrop, J. Weissenbach   +9 more
semanticscholar   +1 more source