Results 21 to 30 of about 294,525 (216)

A new genome scan for primary nonsyndromic vesicoureteric reflux emphasizes high genetic heterogeneity and shows linkage and association with various genes already implicated in urinary tract development

Molecular Genetics & Genomic Medicine, 2014
Primary vesicoureteric reflux (VUR), the retrograde flow of urine from the bladder toward the kidneys, results from a developmental anomaly of the vesicoureteric valve mechanism, and is often associated with other urinary tract anomalies.
J. M. Darlow, M. G. Dobson, R. Darlay, C. M. Molony, M. Hunziker, A. J. Green, H. J. Cordell, P. Puri, D. E. Barton   +8 more
doaj   +1 more source

Annotated genetic linkage maps of Pinus pinaster Ait. from a Central Spain population using microsatellite and gene based markers

BMC Genomics, 2012
Background Pinus pinaster Ait. is a major resin producing species in Spain. Genetic linkage mapping can facilitate marker-assisted selection (MAS) through the identification of Quantitative Trait Loci and selection of allelic variants of interest in ...
de Miguel Marina, de Maria Nuria, Guevara M, Diaz Luis, Sáez-Laguna Enrique, Sánchez-Gómez David, Chancerel Emilie, Aranda Ismael, Collada Carmen, Plomion Christophe, Cabezas José-Antonio, Cervera María-Teresa   +11 more
doaj   +1 more source

Genetic linkage and natural selection [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2010
The prevalence of recombination in eukaryotes poses one of the most puzzling questions in biology. The most compelling general explanation is that recombination facilitates selection by breaking down the negative associations generated by random drift (i.e. Hill–Robertson interference, HRI). I classify the effects of HRI owing to: deleterious mutation,
openaire   +2 more sources

High-density SNP genetic linkage map construction and quantitative trait locus mapping for resistance to cucumber mosaic virus in tobacco (Nicotiana tabacum L.)

Crop Journal, 2019
Genetic linkage maps are essential for studies of genetics, genomic structure, and genomic evolution, and for mapping quantitative trait loci (QTL).
Lirui Cheng, Xiaocui Chen, Caihong Jiang, Bing Ma, Min Ren, Yazeng Cheng, Dan Liu, Ruimei Geng, Aiguo Yang   +8 more
doaj   +1 more source

A genetic linkage study of choroideremia

Ophthalmic Paediatrics and Genetics, 1986
One hundred and twenty-two members of 15 choroideremia families have been used in a genetic linkage study of choroideremia (TCD) using four DNA probes situated on the X chromosome. Linkage was analysed using DNA probes DXS14 (p58-1), DXYS1 (pDP 34), DXS178 (p212) and DXS177 (lambda 2.7).
M, Jay, A F, Wright, J F, Clayton, M, Deans, M, Dempster, S S, Bhattacharya, B, Jay   +6 more
openaire   +3 more sources

An integrated genetic and cytogenetic map for Zhikong scallop, Chlamys farreri, based on microsatellite markers.

PLoS ONE, 2014
The reliability of genome analysis and proficiency of genetic manipulation requires knowledge of the correspondence between the genetic and cytogenetic maps.
Liying Feng, Liping Hu, Xiaoteng Fu, Huan Liao, Xuan Li, Aibin Zhan, Lingling Zhang, Shi Wang, Xiaoting Huang, Zhenmin Bao   +9 more
doaj   +1 more source

Integrating the markers Pan I and haemoglobin with the genetic linkage map of Atlantic cod (Gadus morhua)

BMC Research Notes, 2010
Background Haemoglobin (Hb) and pantophysin (Pan I) markers have been used intensively in population studies of Atlantic cod (Gadus morhua) and in the analysis of traits such as temperature tolerance, growth characteristics and sexual maturation. We used
Simpson Gary, Higgins Brent, Borza Tudor, Bowman Sharen   +3 more
doaj   +1 more source

Genome-wide association and linkage analysis of histidine-rich glycoprotein identifies common variants associated with plasma histidine-rich glycoprotein concentrations

Research and Practice in Thrombosis and Haemostasis
Background: The plasma protein histidine-rich glycoprotein (HRG) interacts with multiple plasma ligands with various roles in coagulation, immunity, and angiogenesis.
Mary I. Underwood, Ayse Bilge Ozel, Tanay Deepak, Beth McGee, Dave Siemieniak, Rida A. Malik, Cherie Teney, Colin A. Kretz, Jeffery Weitz, Karl C. Desch   +9 more
doaj   +1 more source

Construction of a High-Density Genetic Map and Quantitative Trait Locus Mapping in the Manila clam Ruditapes philippinarum

Scientific Reports, 2017
Genetic linkage maps are indispensable tools in a wide range of genetic and genomic research. With the advancement of genotyping-by-sequencing (GBS) methods, the construction of a high-density linkage maps has become achievable in marine organisms ...
Hongtao Nie, Xiwu Yan, Zhongming Huo, Liwen Jiang, Peng Chen, Hui Liu, Jianfeng Ding, Feng Yang   +7 more
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Functional interactions between neurotransmitters and neuropeptides in regulating suprachiasmatic nucleus function and circadian rhythms

Exploration of Neuroscience
The overt expression of circadian rhythms is a manifestation of the suprachiasmatic nucleus (SCN). This integrated complex function based on the transcriptional/translational feedback loops (TFFLs), neurotransmitters, genes, networking, and ...
Vallath Reghunandanan
doaj   +1 more source