Results 51 to 60 of about 3,543,690 (289)

GenAlEx 6.5: genetic analysis in Excel. Population genetic software for teaching and research—an update

Bioinform., 2012
Summary: GenAlEx: Genetic Analysis in Excel is a cross-platform package for population genetic analyses that runs within Microsoft Excel. GenAlEx offers analysis of diploid codominant, haploid and binary genetic loci and DNA sequences.
R. Peakall, P. Smouse
semanticscholar   +1 more source

Construction of a genetic linkage map of the banana fungal pathogen, Mycosphaerella fijiensis, causal agent of Black Sigatoka disease [PDF]

, 2008
The haploid, hemibiotrophic ascomycete fungus Mycosphaerella fijiensis (Morelet) is the causal agent of black Sigatoka, the most economically important disease of banana (Musa spp.). A genetic linkage map of M.
Carlier, Jean, Conde-Ferraez, Laura, James, Andrew C., Luna-Martinez, Francisco, Manzo-Sanchez, Gilberto, Simpson, June, Zapater, Marie-Françoise   +6 more
core  

Impact of template backbone heterogeneity on RNA polymerase II transcription. [PDF]

, 2014
Variations in the sugar component (ribose or deoxyribose) and the nature of the phosphodiester linkage (3'-5' or 2'-5' orientation) have been a challenge for genetic information transfer from the very beginning of evolution.
Chong, Jenny, Huang, Xuhui, Wang, Dong, Wang, Wei, Xu, Liang, Zhang, Lu   +5 more
core   +1 more source

Genetic linkage and natural selection [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2010
The prevalence of recombination in eukaryotes poses one of the most puzzling questions in biology. The most compelling general explanation is that recombination facilitates selection by breaking down the negative associations generated by random drift (i.e. Hill–Robertson interference, HRI). I classify the effects of HRI owing to: deleterious mutation,
openaire   +2 more sources

Functional mapping and annotation of genetic associations with FUMA

Nature Communications, 2017
A main challenge in genome-wide association studies (GWAS) is to pinpoint possible causal variants. Results from GWAS typically do not directly translate into causal variants because the majority of hits are in non-coding or intergenic regions, and the ...
Kyoko Watanabe, E. Taskesen, Arjen van Bochoven, D. Posthuma   +3 more
semanticscholar   +1 more source

Integrating the markers Pan I and haemoglobin with the genetic linkage map of Atlantic cod (Gadus morhua)

BMC Research Notes, 2010
Background Haemoglobin (Hb) and pantophysin (Pan I) markers have been used intensively in population studies of Atlantic cod (Gadus morhua) and in the analysis of traits such as temperature tolerance, growth characteristics and sexual maturation. We used
Simpson Gary, Higgins Brent, Borza Tudor, Bowman Sharen   +3 more
doaj   +1 more source

What does it take to evolve behaviorally complex organisms? [PDF]

, 2001
What genotypic features explain the evolvability of organisms that have to accomplish many different tasks? The genotype of behaviorally complex organisms may be more likely to encode modular neural architectures because neural modules dedicated to ...
Calabretta, Raffaele, Di Ferdinando, Andrea, Parisi, Domenico, Wagner, Günter P.   +3 more
core  

Genome-wide association and linkage analysis of histidine-rich glycoprotein identifies common variants associated with plasma histidine-rich glycoprotein concentrations

Research and Practice in Thrombosis and Haemostasis
Background: The plasma protein histidine-rich glycoprotein (HRG) interacts with multiple plasma ligands with various roles in coagulation, immunity, and angiogenesis.
Mary I. Underwood, Ayse Bilge Ozel, Tanay Deepak, Beth McGee, Dave Siemieniak, Rida A. Malik, Cherie Teney, Colin A. Kretz, Jeffery Weitz, Karl C. Desch   +9 more
doaj   +1 more source

Coalescence, genetic diversity in sexual populations under selection [PDF]

, 2013
In sexual populations, selection operates neither on the whole genome, which is repeatedly taken apart and reassembled by recombination, nor on individual alleles that are tightly linked to the chromosomal neighborhood. The resulting interference between
Kessinger, Taylor A., Neher, Richard A., Shraiman, Boris I.   +2 more
core   +2 more sources

LDlinkR: An R Package for Rapidly Calculating Linkage Disequilibrium Statistics in Diverse Populations

Frontiers in Genetics, 2020
Genomic research involving human genetics and evolutionary biology relies heavily on linkage disequilibrium (LD) to investigate population-specific genetic structure, functionally map regions of disease susceptibility and uncover evolutionary history ...
Timothy A. Myers, S. Chanock, M. Machiela   +2 more
semanticscholar   +1 more source