Results 111 to 120 of about 571,568 (315)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

A second generation genetic linkage map for silver carp (Hypophthalmichehys molitrix) using microsatellite markers

, 2013
In the study, we constructed a second generation genetic linkage map for silver carp (Hypophthalmichthys molitrix) using anonymous and EST-derived microsatellite markers in a mapping panel containing 156 "pseudo BC" progenies from two interspecific ...
He, Shunping, Tong, Jingou, Feng, Xiu, Wang, Xinhua, Zeng, Fanzhen, Zhu, Chuankun, Guo, Wenjie, Fu, Beide, Tong, JG (reprint author), Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China., Liu, Lusha, Yu, Xiaomu, Liu, Haiyang   +11 more
core   +1 more source

Cosmopolitan linkage disequilibrium maps

Human Genomics, 2005
Linkage maps have been invaluable for the positional cloning of many genes involved in severe human diseases. Standard genetic linkage maps have been constructed for this purpose from the Centre d'Etude du Polymorphisme Humain and other panels, and have ...
Gibson Jane, Tapper William, Zhang Weihua, Morton Newton, Collins Andrew   +4 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

An integrated genetic linkage map for white clover (Trifolium repens L.) with alignment to Medicago

, 2013
Background: White clover (Trifolium repens L.) is a temperate forage legume with an allotetraploid genome (2n=4×=32) estimated at 1093 Mb. Several linkage maps of various sizes, marker sources and completeness are available, however, no integrated map ...
Franzmayr, Benjamin K, Griffiths, Andrew G, Simon, Deborah, Khan, Anar K, Hancock Kerry R., Barrett, Brent A, Bickerstaff, Paul, Jones, Chris S, Anderson, Craig B   +8 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

A second-generation genetic linkage map for bighead carp (Aristichthys nobilis) based on microsatellite markers

, 2014
Bighead carp (Aristichthys nobilis) is an important aquaculture fish worldwide. Genetic linkage maps for the species were previously reported, but map resolution remained to be improved.
Yu, X., Liu, L., Tong, J., Fu, B., Zhu, C., Liu, H., Wang, X., Sun, Y., Guo, W., Feng, X.   +9 more
core   +1 more source

Identificação de QTL associados à simbiose entre Bradyrhizobium japonicum, B. elkanii e soja Identification of QTL associated with the symbiosis of Bradyrhizobium japonicum, B. elkanii and soybean

Pesquisa Agropecuária Brasileira, 2006
O objetivo deste trabalho foi identificar QTL (locos de caráter quantitativo), utilizando marcadores do tipo microssatélites (SSR), relacionados à fixação biológica de nitrogênio (FBN), em uma população F2:7 de cultivares de soja (Glycine max) com ...
Maria Aparecida dos Santos, Marisa Fabiana Nicolás, Mariangela Hungria   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source