Results 111 to 120 of about 4,786,280 (310)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Clason's Guide to Texas: With Map of Auto Routes

open access: yes, 1917
Map of the state of Texas and surrounding areas. Individual counties are outlined in green and labeled with roads marked in red and railroads marked in black. Geographic features are marked with relief shown by hachures.
Clason Map Co.
core  

Construction of the First Genetic Linkage Map and QTL Analysis for Morphological Traits in Bougainvillea glabra Choisy

open access: yesPlants
Bougainvillea (Bougainvillea glabra) is a perennial woody species belonging to the Nyctaginaceae family, native to South America. It is widely recognized for its brightly colored bracts and strong adaptability, and is widely cultivated as a major ...
Yaru Wang   +9 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

China proper SE 1:250,000 [cartographic material] /

open access: yes, 1944
Map series of the southeastern corner of China showing international, province and district boundaries, transportation, water features, walls, rice fields and populated places.
United States. Army Map Service.
core  

Genome-wide SSR marker development and application in molecular breeding of Hemerocallis

open access: yesFrontiers in Plant Science
The Hemerocallis genus belongs to the Asphodelaceae family and is a perennial herbaceous plant. To facilitate molecular breeding and industrial development in Hemerocallis, this study developed genome-wide simple sequence repeat (SSR) markers based on ...
Feifan Hou   +12 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Truk Islands : special strategic map

open access: yes, 1945
Scale 1:1,000,000 ; Lambert conformal conic projection. 1 map : color ; 46 x 68 cm. First edition-AMS 1. Prepared under the direction of the Chief of Engineers, U.S. Army ; compiled by the Army Map Service, February 1943. Standard map series designation:
United States. Army Map Service.
core  

Sexagesimal scale for mapping human genome Escala sexagesimal para mapear el genoma humano

open access: yesRevista Chilena de Historia Natural, 2001
In a previous work I designed a diagram of the human genome based on a circular ideogram of the haploid set of chromosomes, using a low resolution scale of Megabase units.
RICARDO CRUZ-COKE
doaj  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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