Results 71 to 80 of about 4,786,280 (310)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Genome-Wide Mapping Reveals Major and Stable Quantitative Trait Loci for Seed Oil Content in Soybean

open access: yesAgronomy
Seed oil content is one of the primary breeding objectives in soybean. However, the genetic basis of seed oil content remains largely unexplored. In this study, we employed a recombinant inbred line (RIL) population consisting of 201 lines derived from a
Shuguang Li   +7 more
doaj   +1 more source

Statistical Methods in Genetic Mapping

open access: yesGenomics, 1994
This report describes the proceedings from the second Workshop on Statistical Methods in Genetic Mapping, held in Tarrytown, NY on November 13-15, 1995. The workshop was supported by a grant from the National Center for Human Genome Research and covered a wide variety of topics pertaining to genetic mapping methods, integration and concerns. 25 refs.
J, Ott, H, Donis-Keller
openaire   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

A high-density consensus map of barley linking DArT markers to SSR, RFLP and STS loci and agricultural traits [PDF]

open access: yes, 2006
Background: Molecular marker technologies are undergoing a transition from largely serial assays measuring DNA fragment sizes to hybridization-based technologies with high multiplexing levels.
Wenzl Peter   +67 more
core   +2 more sources

Genetic Variation for Protein Content and Yield-Related Traits in a Durum Population Derived From an Inter-Specific Cross Between Hexaploid and Tetraploid Wheat Cultivars

open access: yesFrontiers in Plant Science, 2019
Wheat grain protein content (GPC) and yield components are complex quantitative traits influenced by a multi-factorial system consisting of both genetic and environmental factors.
Angelica Giancaspro   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Indochina 1:50,000 [cartographic material] /

open access: yes, 1960
Ed. 3-AMS. Map series of Cambodia showing roads, state and provincial boundaries, buildings, communications, religious sites, bridges, ground and water features, vegetation and cultivation.
United States. Army Map Service.
core  

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