Results 191 to 200 of about 4,905,945 (358)

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Genetic Markers of Postmortem Brain Iron. [PDF]

J Neurochem
Cornelis MC, Fazlollahi A, Bennett DA, Schneider JA, Ayton S.   +4 more
europepmc   +1 more source

Structural differences in a single gene encoding the V kappa Ser group of light chains explain the existence of two mouse light-chain genetic markers.

, 1986
R. Thomas Boyd, Marianna Goldrick, Paul Gottlieb   +2 more
openalex   +1 more source

Mapping migration in a songbird using high-resolution genetic markers

bioRxiv, 2014
Kristen C. Ruegg, E. Anderson, K. Paxton, Vanessa E. Apkenas, Sirena Lao, R. Siegel, D. Desante, F. Moore, T. Smith   +8 more
semanticscholar   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Genetic markers involved in neuroinflammation in Down syndrome: a systematic review. [PDF]

Dement Neuropsychol
Silva MN, Lula MD, Felício LR, Santos B, Nassif LS, Borin MC, Alvares-Teodoro J, Acurcio FA, Guerra AA.   +8 more
europepmc   +1 more source

Characteristics of the Mongoloid and Neighboring Populations on the Basis of the Genetic Markers of Immunoglobulins

, 1987
Hideo Matsumoto
openalex   +2 more sources

Ultraconserved elements anchor thousands of genetic markers spanning multiple evolutionary timescales.

Systematic Biology, 2012
B. Faircloth, J. McCormack, Nicholas G. Crawford, Michael G. Harvey, R. T. Brumfield, T. Glenn   +5 more
semanticscholar   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Genetic markers of early response to lurasidone in acute schizophrenia. [PDF]

Pharmacogenomics J
Yoshikawa A, Li J, Alliey-Rodriguez N, Meltzer HY.   +3 more
europepmc   +1 more source