Results 191 to 200 of about 5,022,316 (352)
Molecular and Genetic Markers for Malignant Melanoma: Implications for Prognosis and Therapy. [PDF]
Fleshner L +6 more
europepmc +1 more source
In the blood: the myth and reality of genetic markers of identity
M. Jobling, Rita Rasteiro, J. Wetton
semanticscholar +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Variability Survey at Different Genetic Markers as Effective Tools for the Management of the Endangered Breeds: The Case of the Sicilian Native Donkeys. [PDF]
Carlentini M +7 more
europepmc +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Genetic Markers and Mutations in Primary Spinal Cord Tumors and Their Impact on Clinical Management. [PDF]
Motiei-Langroudi R.
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Modelling the Consequences of Domestication-Introgression in Wild Populations Using Genetic Markers Under Varying Degrees of Selection. [PDF]
Glover KA +3 more
europepmc +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source

