Results 201 to 210 of about 1,070,803 (312)

Genetic Markers and Mutations in Primary Spinal Cord Tumors and Their Impact on Clinical Management. [PDF]

Brain Sci
Motiei-Langroudi R.
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Development and Characterization of Microsatellite Genetic Markers for <i>Hyalomma rufipes</i>, a Tick Vector of Crimean-Congo Hemorrhagic Fever Virus. [PDF]

Ecol Evol
Ahmad H, Aool W, Anyango V, Nakayaki TM, Mulwa F, Chelangat B, Lutwama JJ, Kayondo JK, Lukindu M, Mutisya J, Lutomiah J, Hensley LE, Cohnstaedt LW, Onyango MG, Brelsfoard CL.   +14 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Correction for Liao et al., Noncanonical genetic markers resolve the pre-GOE emergence of aerobic bacteria in Earth's history. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Variability Survey at Different Genetic Markers as Effective Tools for the Management of the Endangered Breeds: The Case of the Sicilian Native Donkeys. [PDF]

Animals (Basel)
Carlentini M, Tumino S, Chessari G, Antoci A, Criscione A, Marletta D, Mastrangelo S, Bordonaro S.   +7 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Serological and genetic markers in gastric polyps: Diagnostic and prognostic roles of pepsinogen, gastrin-17, and ABO antigens. [PDF]

Medicine (Baltimore)
Gao Q, He X, Li H, Yan H, Wu L, Zhong P, Tang J.   +6 more
europepmc   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

'Highly-Informative' Genetic Markers Can Bias Conclusions: Examples and General Solutions. [PDF]

Mol Ecol Resour
Lee A, Hemstrom W, Molea N, Luikart G, Christie MR.   +4 more
europepmc   +1 more source