Results 211 to 220 of about 1,557,985 (257)
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Genetic Instability Markers in Cancer
2019High frequency of mutations seems to determine a higher occurrence of neoepitope formation and, thus, tumor immunogenicity. A somatic hypermutated status could thus act as a predictive biomarker of responsiveness to immunotherapy with recent immune checkpoint inhibitors.
Palmieri Giuseppe +7 more
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Human Heredity, 1981
In a study of genetic markers in patients with epilepsy, 30 genetic systems have been tested and the results compared with all previously published studies on this subjects. Only one marker, Ss + ss/SS in the MNSs blood group system showed a statistically highly significant difference (p below 0.001) in the epileptic patients compared with a control ...
A. Warlow +3 more
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In a study of genetic markers in patients with epilepsy, 30 genetic systems have been tested and the results compared with all previously published studies on this subjects. Only one marker, Ss + ss/SS in the MNSs blood group system showed a statistically highly significant difference (p below 0.001) in the epileptic patients compared with a control ...
A. Warlow +3 more
openaire +2 more sources
Genetic Markers of Alzheimer’s Disease
2019Alzheimer's disease is a complex and heterogeneous, severe neurodegenerative disorder and the predominant form of dementia, characterized by cognitive disturbances, behavioral and psychotic symptoms, progressive cognitive decline, disorientation, behavioral changes, and death.
Nela Pivac, Matea Nikolac Perkovic
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Genetic Markers and Biotechnology
2015Clusterbean is an obligatory self-pollinating and inbreeding species and therefore, little variation in DNA polymorphism is expected among the cultivars. It has triploid endosperm and has more vegetative growth as compared to diploid counterparts.
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Psoriasis vulgaris and genetic markers
Human Genetics, 1977In a sample of n = 160 nonrelated male and female patients suffering from psoriasis Vulgaris, blood serum protein, and enzyme group typings have been carried out and compared with healthy controls from the same area (Rheinland-Pfalz). Marked statistically significant differences between patients and controls were found in none of the genetic blood ...
Maria Hilling +3 more
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Genetic and immunological markers in pouchitis
European Journal of Gastroenterology & Hepatology, 1996Previous studies of the interleukin-1 receptor antagonist (IL-1RN) have found an increased frequency of the associated variable number tandem repeat (VNTR) allele 2 for ulcerative colitis (UC) and further evidence has been reported that this allele is associated with increased severity of several other inflammatory conditions.
JY Yiannakou +7 more
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Genetic markers in methotrexate treatments
The Pharmacogenomics Journal, 2018Methotrexate (MTX), a structural analog of folic acid, is widely employed in the treatment of different cancers and autoimmune diseases. Despite the successful results observed, the main disadvantage lies in interpatient variability in the pharmacokinetic and pharmacodynamic parameters.
Andrea Giletti, Patricia Esperon
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Genetic Markers in Carcinoma of the Prostate
European Urology, 1984The distribution of phenotypes and gene frequencies of the third component of complement (C3), group-specific component (Gc), haptoglobin (Hp) and transferrin (Tf) were studied in 115 patients with carcinoma of the prostate. The statistical analysis of our findings in comparison to the frequency of these genes in a control group of 155 patients with ...
Germenis, A +5 more
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Genetic markers and cancer epidemiology
Cancer, 1977The study of potential associations between genetic markers and various cancers has a long history in cancer epidemiology. Such investigations are subject to serious problems of statistical significance and the choice of appropriate control populations.
Mary Claire King +2 more
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