Results 91 to 100 of about 3,369,685 (306)

Genetic modification of milk proteins [PDF]

open access: yesThe American Journal of Clinical Nutrition, 1996
It is now possible to change the protein composition of milk by direct manipulation of the germline. At present it is feasible only to add new milk-protein genes to dairy animals. If embryonic stem cells become available then it will also be possible to remove or replace endogenous genes.
openaire   +2 more sources

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh   +4 more
wiley   +1 more source

Secondary plant metabolites as targets for genetic modification of crop plants for pest resistance.

open access: yes, 1989
Three genetic manipulation strategies are described for enhancing the effectiveness of secondary metabolites of crop plants in reducing pest and disease damage. Targets for gene transfer studies are secondary metabolites of oilseed rape, lepidopteran sex
Pickett, J. A.   +12 more
core   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba   +29 more
wiley   +1 more source

RETRACTED: Genetic modification: A tool for enhancing beta-glucosidase production for biofuel application

open access: yes
Beta-glucosidase (BGL) is a rate-limiting enzyme for cellulose hydrolysis as it acts in the final step of lignocellulosic biomass conversion to convert cellobiose into glucose, the final end product.
Singhania, Reeta Rani   +3 more
core   +1 more source

Genetic modifications in cardiology: the role of CRISPR-Cas9 in the treatment of cardiovascular diseases

open access: yesКлинический разбор в общей медицине
Introduction. Cardiovascular diseases (CVD) continue to be the leading cause of death worldwide. The development of new therapeutic approaches that can more accurately affect the molecular mechanisms of CVD is extremely important. Recent breakthroughs in
Tatyana A. Gretseva   +14 more
doaj   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine   +21 more
wiley   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak   +9 more
wiley   +1 more source

Advances in the production of fungi-derived lignocellulolytic enzymes using agricultural wastes

open access: yesMycology
Lignocellulolytic enzymes play an important role in various industrial applications as well as the sustainable valorisation of lignocellulosic materials.
Jiaqi Huang, Jianfei Wang, Shijie Liu
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

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