Results 101 to 110 of about 3,369,685 (306)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

097: The Evolutionary Modification of Genetic Phenomena.

, 1932
No abstract .
Fisher, R. A., Fisher, Ronald Aylmer, Sir, 1890-1962   +1 more
core  

An Economic Analysis of Risk, Management, and Agricultural Technology

Journal of Agricultural and Resource Economics, 2015
This paper uses conditional quantile regression to analyze the effects of genetically modified (GM) seed technology and management on production risk in agriculture, with an application to the distribution of corn yield in Wisconsin.
Jean-Paul Chavas, Guanming Shi
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

No Oral Modification Clauses: Solid as a Rock [PDF]

, 2019
This is an analysis of the 2018 UK Supreme Court case Rock Advertising Ltd v MWB Business Exchange Centres Ltd, which concerned the legal validity of No Oral Modification ...
Dodd, Leslie
core  

Genetic influences on exercise participation in 37.051 twin pairs from seven countries [PDF]

, 2006
Background A sedentary lifestyle remains a major threat to health in contemporary societies. To get more insight in the relative contribution of genetic and environmental influences on individual differences in exercise participation, twin samples from ...
Hunkin, J, Boomsma, Dorret I, Spector Tim D., Kaprio J, Nicholas G. Martin, Martin NG, Harris, Jennifer R., de Geus, Eco J. C, Belinda K. Cornes, Rose, Richard J., Eco J. C. De Geus, de Geus, E.J.C., Stubbe JH, Dorret I. Boomsma, Richard J, Harris JR, Stubbe Janine H., Kyvik, KO, Rose RJ, Pedersen, Nancy L., Martin, N.G., de Geus EJ, Tim D Spector, de Geus Eco J.C., Boomsma, Dorret I., Pedersen, Nancy L, Nancy L Pedersen, Cornes, Belinda K, Kaprio, Jaakko, Skytthe A, Martin, Nicholas G., Stubbe, Janine H., Kyvik, K., Vink, JM, Hunkin Janice, Rose, Richard J, Rose, RJ, Jacqueline M. Vink, Vink JM, Skytthe, Axel, Pedersen NL, Dorret I Boomsma, Vink, J.M., Hunkin, J., Vink, Jacqueline M., de Geus, EJC, Kujala, Urho M, Jennifer R Harris, Kyvik KO, Boomsma DI, Boomsma, DI, Kujala UM, Cornes, Belinda K., Kaprio, J., Kyvik, Kirsten O., Richard J Rose, Jennifer R. Harris, Axel Skytthe, Spector, Tim D, Nancy L. Pedersen, Rose Richard J., Kujala, UM, Stubbe, JH, Skytthe, A, Eco J C de Geus, Kirsten O. Kyvik, Kyvik Kirsten O., Harris Jennifer R., Janice Hunkin, Boomsma Dorret I., Skytthe Axel, Vink Jacqueline M., Spector TD, Kirsten O Kyvik, Kujala, U., Kaprio Jaakko, Stubbe, Janine H, Pedersen, N.L., Martin, NG, Kujala, Urho M., Cornes Belinda K., Urho M. Kujala, Harris, Jennifer R, Spector, T.D., Jaakko Kaprio, Pedersen, NL, Stubbe, J.H., Boomsma, D.I., Martin Nicholas G., Cornes BK, Tim D. Spector, de Geus, E.J.C.; id_orcid, de Geus, EJ, Harris, JR, Vink, Jacqueline M, Kyvik, Kirsten O, Cornes, B., Belinda K Cornes, Urho M Kujala, Rose, R.J., Spector, Tin D., Skytthe, A., Pedersen Nancy L., Martin, Nicholas G, Kaprio, J, Janine H Stubbe, Cornes, BK, De Geus, Eco J. C., Hunkin J, Nicholas G Martin, Jacqueline M Vink, Spector, TD, Hunkin, Janice, Boomsma, D.I.; id_orcid, Harris, J.R., Janine H. Stubbe, Kujala Urho M.   +116 more
core   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Genetic modification Risks and safeguards

, 1995
SIGLEAvailable from British Library Document Supply Centre- DSC:GPC/08279 / BLDSC - British Library Document Supply CentreGBUnited ...
Health and Safety Commission (United Kingdom). Advisory Committee on Genetic Modification
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source