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Genetic modification and genetic determinism
In this article we examine four objections to the genetic modification of human beings: the freedom argument, the giftedness argument, the authenticity argument, and the uniqueness argument.
Vorhaus Daniel B, Resnik David B
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Genetic modification of hypertension by sGCα1 [PDF]
Hypertension is an important modifiable risk factor for coronary heart disease, congestive heart failure, stroke, end-stage renal disease, and peripheral vascular disease, but many of the molecular mechanisms and genetic factors underlying the development of the most common forms of human hypertension remain to be defined.
Sips, Patrick, Buys, Emmanuel
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Advances in robotic system-assisted genome editing techniques and computer-aided design tools have significantly facilitated the development of microbial cell factories. Although multiple separate software solutions are available for vector DNA assembly,
Yi Yang +16 more
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Biotechnology Advances in Bioremediation of Arsenic: A Review
Arsenic is a highly toxic metalloid widespread in the Earth's crust, and its contamination due to different anthropogenic activities (application of agrochemicals, mining, waste management) represents an emerging environmental issue. Therefore, different
Jaganathan Sakthi Yazhini Preetha +5 more
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Genetic modification in humans, non-human animals, and plants gives rise to a range of philosophical and ethical issues. There are a range of techniques and applications for genetic modification, but all are intended to change the genome within the cells of an organism.
Wrigley, AJ, Newson, A
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Major progress has been made over the last decade in identifying novel genes involved in neurodevelopmental disorders, although the task of elucidating their corresponding molecular and pathophysiological mechanisms, which are an essential prerequisite ...
Hamid Meziane +13 more
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A Nectin1 Mutant Mouse Model Is Resistant to Pseudorabies Virus Infection
The present study generated nectin1-mutant mice with single amino acid substitution and tested the anti-pseudorabies virus (PRV) ability of the mutant mice, with the aim to establish a model for PRV-resistant livestock.
Xiaohui Yang +11 more
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Resistance to Plum pox virus (PPV) in transgenic Prunus domestica L., clone C5 (cv. HoneySweet) was evaluated in a regulated field in the Czech Republic for fifteen years (2002-2016). PPV mild symptoms appeared in C5 trees only in several leaves situated
Jaroslav Polák +3 more
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Genetic Modification of T Cells
Adoptively transferred T cells have shown activity in treating viral infections after hemopoietic transplantation and anti-tumor activity against some malignancies such as melanoma and lymphoma. Current research focuses on defining the optimum type of cell for transfer to improve persistence and genetically modifying infused T cells to augment function,
BONINI , MARIA CHIARA +3 more
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Mesenchymal stem/stromal cells (MSCs) have the ability to secrete bioactive molecules, exerting multiple biological effects, such as tissue regeneration, reduction of inflammation, and neovascularization.
Girlaine Café Santos +17 more
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