Results 11 to 20 of about 3,369,685 (306)

Genetic modification and genetic determinism

open access: yesPhilosophy, Ethics, and Humanities in Medicine, 2006
In this article we examine four objections to the genetic modification of human beings: the freedom argument, the giftedness argument, the authenticity argument, and the uniqueness argument.
Vorhaus Daniel B, Resnik David B
doaj   +4 more sources

Genetic Modification of Brain Organoids [PDF]

open access: yesFrontiers in Cellular Neuroscience, 2019
Brain organoids have become increasingly used systems allowing 3D-modeling of human brain development, evolution, and disease. To be able to make full use of these modeling systems, researchers have developed a growing toolkit of genetic modification ...
Jan Fischer   +2 more
doaj   +5 more sources

Genetic Modification [PDF]

open access: yes, 2021
Genetic modification in humans, non-human animals, and plants gives rise to a range of philosophical and ethical issues. There are a range of techniques and applications for genetic modification, but all are intended to change the genome within the cells
Wrigley, A, Newson, A
core   +2 more sources

Genetic modification of hypertension by sGCα1 [PDF]

open access: yesTrends in Cardiovascular Medicine, 2013
Hypertension is an important modifiable risk factor for coronary heart disease, congestive heart failure, stroke, end-stage renal disease, and peripheral vascular disease, but many of the molecular mechanisms and genetic factors underlying the development of the most common forms of human hypertension remain to be defined.
Sips, Patrick, Buys, Emmanuel
openaire   +4 more sources

Regulating inheritable genetic modification or policing the fertile scientific imagination? : a feminist legal response. [PDF]

open access: yes, 2006
The past few years have seen an explosion of legislative activity around developments in genetics and assisted reproduction. In this chapter we examine recently passed legislation in Australia and Canada in the area of genetic modification technologies ...
Karpin, Isabel, Mykitiuk, Roxanne
core   +2 more sources

Ecological modernization versus sustainable development: the case of genetic modification regulation in New Zealand [PDF]

open access: yes, 2009
Ecological modernization and sustainable development are the two dominant paradigms in environmental policy. This paper assesses the implications of competing understandings of ecological modernization and sustainable development using the case of ...
Wright, Jeanette Marie   +3 more
core   +1 more source

Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models

open access: yesBiomedicines, 2022
Major progress has been made over the last decade in identifying novel genes involved in neurodevelopmental disorders, although the task of elucidating their corresponding molecular and pathophysiological mechanisms, which are an essential prerequisite ...
Hamid Meziane   +13 more
doaj   +1 more source

A Nectin1 Mutant Mouse Model Is Resistant to Pseudorabies Virus Infection

open access: yesViruses, 2022
The present study generated nectin1-mutant mice with single amino acid substitution and tested the anti-pseudorabies virus (PRV) ability of the mutant mice, with the aim to establish a model for PRV-resistant livestock.
Xiaohui Yang   +11 more
doaj   +1 more source

Reaction of transgenic plum cv. HoneySweet to the Plum pox virus after a severe infection of Monilinia sp. - short communication

open access: yesPlant Protection Science, 2019
Resistance to Plum pox virus (PPV) in transgenic Prunus domestica L., clone C5 (cv. HoneySweet) was evaluated in a regulated field in the Czech Republic for fifteen years (2002-2016). PPV mild symptoms appeared in C5 trees only in several leaves situated
Jaroslav Polák   +3 more
doaj   +1 more source

Genetic Modification of T Cells

open access: yesBiology of Blood and Marrow Transplantation, 2011
Adoptively transferred T cells have shown activity in treating viral infections after hemopoietic transplantation and anti-tumor activity against some malignancies such as melanoma and lymphoma. Current research focuses on defining the optimum type of cell for transfer to improve persistence and genetically modifying infused T cells to augment function,
BONINI , MARIA CHIARA   +3 more
openaire   +2 more sources

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