Results 161 to 170 of about 418,825 (313)

Correlational parameter tuning by genetic meta-algorithm [PDF]

open access: yes, 2000
The general problem of an off-line parameter tuning in the Binary Genetic Algorithm (BGA) is introduced. An example of such a tuning: a class of Correlational Tuning Methods (CTMs) is proposed.
Kosiński, W., Kieś, P.
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Optimisation of the hydrotesting sequence in tank farm construction using an adaptive genetic algorithm with stochastic preferential logic [PDF]

open access: yes, 2008
In the construction of tank farms there is a requirement for the tanks to be hydro-tested in order to verify that they are leak proof as well as proving the lack of differential settlement in the foundations.
Cheng, K, Lancaster, J
core  

Astrocyte heterogeneity in brain metastases

open access: yesMolecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver   +2 more
wiley   +1 more source

Setting Parameter Single Machine Infinite Bus Via Genetic Algorithm [PDF]

open access: yes, 2009
Paper ini mempresentasikan metode penalaan parameter untuk mendapatkan performansi yang optimumdari sebuah Single Machine Infinite Bus (SMIB).Genetic Algorithm (GA) digunakan sebagai metode pencarian parameter parameter yang sesuai dariSMIB tersebut ...
Kharisma, Bedy, Robandi, Imam
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Genetic parameter analysis of bareness and tail traits in New Zealand sheep. [PDF]

open access: yesJ Anim Sci, 2023
Johnson PL   +5 more
europepmc   +1 more source

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