Results 181 to 190 of about 3,837,457 (288)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Genetic Parameter Estimates and Associations Between Clutch Length and Hen-Day Egg Production Traits in Thai Native Chickens Under Heat Stress. [PDF]

Animals (Basel)
Sungkhapreecha P, Chankitisakul V, Boonkum W.   +2 more
europepmc   +1 more source

Phenotypic and genetic parameter estimates for early growth, growth rate and growth efficiency-related traits of Fogera cattle in Ethiopia. [PDF]

Vet Med Sci, 2022
Kassahun D, Taye M, Kebede D, Tilahun M, Tesfa A, Bitew A, Kebede A, Meseret M, Lakew E, Bimrow T, Haile A.   +10 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Application of Genomic Random Regression Models for Genetic Parameter Estimations of Female Fertility Traits in Different Parities in German Holsteins. [PDF]

J Anim Breed Genet
Sakhaei-Far S, Yin T, König S.
europepmc   +1 more source

Genetic Parameter Estimation and Genome-Wide Association Study-Based Loci Identification of Milk-Related Traits in Chinese Holstein. [PDF]

Front Genet, 2021
Lu X, Arbab AAI, Abdalla IM, Liu D, Zhang Z, Xu T, Su G, Yang Z.   +7 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Genetic Parameter Estimation for Pregnancy Loss and Their Association With Reproductive and Growth Traits in Brahman Cattle Under Extensive Tropical Conditions. [PDF]

J Anim Breed Genet
Cardona-Cifuentes D, de Albuquerque LG, Arias M, Caivio-Nasner S, Camaripano L, Gonzalez-Herrera LG, Schmidt PI, Baldi F.   +7 more
europepmc   +1 more source

Genetic parameter estimates for bull prolificacy and its relationship with scrotal circumference in a commercial beef cattle population. [PDF]

Transl Anim Sci, 2021
Russell CA, Pollak EJ, Spangler ML.
europepmc   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source