Results 101 to 110 of about 12,859,837 (351)

Fractal Characterizations of MAX Statistical Distribution in Genetic Association Studies

, 2009
Two non-integer parameters are defined for MAX statistics, which are maxima of $d$ simpler test statistics. The first parameter, $d_{MAX}$, is the fractional number of tests, representing the equivalent numbers of independent tests in MAX.
Azzalini A., Heisenberg W., Mao J., Press W. H., Sham P., Sokal R. K., Thomas D. C., Weir B. S.   +7 more
core   +1 more source

Assessment of the dynamics of microparasite infections in genetically homogeneous and heterogeneous populations using a stochastic epidemic model [PDF]

, 2008
The aim of this paper was to explore the effect of genetic heterogeneity in host resistance to infection on the population-level risks and outcomes of epidemics.
Bishop, S. C., Nath, M., Woolliams, J. A.   +2 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Estimates of genetic parameters of wood traits for sawn timber production in Eucalyptus grandis

Genetics and Molecular Biology, 2004
In this study, the breeding perspectives of 41 open-pollinated progenies of Eucalyptus grandis were evaluated based on their wood traits. The progenies were distributed in two experiments in a randomized complete block design, with three replicates and ...
Paulo Eduardo Telles dos Santos, Isaias Olívio Geraldi, José Nivaldo Garcia   +2 more
doaj   +1 more source

Genetic Algorithm for Orthogonal Designs [PDF]

, 2006
We show how to use Simple Genetic Algorithm to produce Hadamard matrices of large orders, from teh full orthogonal design or oder 16 with 9 variables, OD(16; 1, 1, 2, 2, 2, 2, 2, 2, 2).
Cousineau, Jason, Kotsireas, Ilias S., Koukouvinos, Christos   +2 more
core   +1 more source

Age-related trends in genetic parameters for Larix kaempferi and their implications for early selection

BMC Genetics, 2014
Japanese larch (Larix kaempferi) has been introduced in China at the end of the 19th century, and as one successful exotic species, is becoming the preferred coniferous in northern China and sub-tropical alpine region.
Meng Lai, Xiaomei Sun, Dongsheng Chen, Yunhui Xie, Shougong Zhang   +4 more
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Growth Curves and Genetic Parameters in Colombian Buffaloes (Bubalus bubalis Artiodactyla, Bovidae) Curvas de crecimiento y parámetros genéticos en búfalos (Bubalus bubalis Artiodactyla, Bovidae) en Colombia Curvas de crescimento e parâmetros genéticos em búfalos (Bubalus bubalis Artiodactyla, Bovidae) na Colômbia

Revista Colombiana de Ciencias Pecuarias, 2009
Non-linear mathematical functions proposed by Brody, Gompertz, Richards, Bertalanffy and Verhulst were compared in several buffalo production systems in Colombia. Herds were located in three provinces: Antioquia, Caldas, and Cordoba.
Divier Agudelo-Gómez, Naudín Hurtado-Lugo, Mario F Cerón-Muñoz   +2 more
doaj  

Componentes de (co)variância e parâmetros genéticos de características de crescimento da raça Simental no Brasil Variance components and genetic parameters estimates for growth traits of Simmental cattle in Brazil

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 1999
Informações de genealogia e produção, cedidas pela Associação Brasileira de Criadores da Raça Simental (ABCRS), relativas aos pesos desde o nascimento até um ano de idade, foram utilizadas para estimar, sob modelos alternativos, os componentes de ...
L.F.A. Marques, J.C.C. Pereira, H.N. Oliveira, C.S. Pereira, J.A.G. Bergmann   +4 more
doaj   +1 more source