Results 111 to 120 of about 12,859,837 (351)

Genetic Parameters for Fertility of Dairy Bulls

Journal of Dairy Science, 1988
Genetic parameters for male fertility and fertility ratings of AI bulls were obtained by analyzing 298,013 service records of cows with successive calving records. Cows were mated to 746 service bulls, which were progeny of 126 sires. The model for variance component estimation accounted for fixed effects of herd-year-seasons, sire of the service bull,
K, Nadarajah, E B, Burnside, L R, Schaeffer   +2 more
openaire   +2 more sources

Genomic Relationship Matrix for Correcting Pedigree Errors in Breeding Populations: Impact on Genetic Parameters and Genomic Selection Accuracy

, 2014
Quantitative genetic analyses aim to estimate genetic parameters and breeding values to select superior parents, families, and individuals. For these estimates a relationship matrix derived from the pedigree typically is used in a mixed model framework ...
P. Muñoz, Marcio F. R. Resende, D. Huber, Tania Quesada, M. Resende, D. Neale, J. Wegrzyn, M. Kirst, Gary F. Peter   +8 more
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Estimates of heritability and genetic correlations for milk coagulation properties and individual laboratory cheese yield in Sarda ewes

Animal, 2017
Objective of this study was to estimate genetic parameters of milk coagulation properties (MCPs) and individual laboratory cheese yield (ILCY) in a sample of 1018 Sarda breed ewes farmed in 47 flocks. Rennet coagulation time (RCT), curd-firming time (k20)
A. Puledda, G. Gaspa, M.G. Manca, J. Serdino, P.P. Urgeghe, C. Dimauro, R. Negrini, N.P.P. Macciotta   +7 more
doaj   +1 more source

Genetic Parameters for Limousine Interbeef Genetic Evaluation of Calving Traits

Genes
The aim of this study was to estimate across-country genetic correlations for calving traits (birth weight, calving ease) in the Limousine breed. Correlations were estimated for eight populations (Czech Republic, joint population of Denmark, Finland, and Sweden, France, Great Britain, Ireland, Slovenia, Switzerland, and Estonia). An animal model on raw
Zdeňka Veselá, Michaela Brzáková, Alexandra Novotná, Luboš Vostrý   +3 more
openaire   +2 more sources

The evolution of phenotypes and genetic parameters under preferential mating

Ecology and Evolution, 2014
This article extends and adds more realism to Lande's analytical model for evolution under mate choice by using individual-based simulations in which females sample a finite number of males and the genetic architecture of the preference and preferred ...
D. Roff, D. Fairbairn
semanticscholar   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Phenotypic variance of black oat growing in crop seasons reveals genetic effects predominance

Anais da Academia Brasileira de Ciências
: This work aimed to determine variance components and genetic parameters, as well as phenotypic, genetic and environmental correlations among black oat (Avena strigosa) families grown in different crop season.
DANIELA MEIRA, CARINE MEIER, TIAGO OLIVOTO, MAICON NARDINO, ALEXSANDER RIGATTI, LUÍS ANTÔNIO KLEIN, BRAULIO O. CARON, VOLMIR S. MARCHIORO, VELCI Q. DE SOUZA   +8 more
doaj   +1 more source

Genetic parameters for earnings in Quarter Horse

Genetics and Molecular Research, 2014
In this study, we estimated the heritability (h(2)) of earnings in the Quarter Horse in order to evaluate the inclusion of this trait in breeding programs. Records from 14,754 races of 2443 horses from 1978-2009 were provided by Sorocaba Hippodrome, São Paulo, Brazil.
Silva, A. P. A., Curi, Rogerio Abdallah, Langlois, B., Silva, J. A. H. V.   +3 more
openaire   +5 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source