Results 101 to 110 of about 666,141 (292)

Real‐world Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

Arthritis Care &Research, Accepted Article.
Objectives Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), yet the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to: 1) identify clinical factors that predict ...
Jay J. Patel, Fauzia Hollangel MPH, Caroline Packee, Amita Kapoor, Brad Rovin, Nathalie Costedoat‐Chalumeau, Shivani Garg   +6 more
wiley   +1 more source

Influence of socioeconomic lifestyle factors and genetic polymorphism on type 2 diabetes occurrences among Tunisian Arab and Berber groups of Djerba Island

Pharmacogenomics and Personalized Medicine, 2009
Thouraya Baroudi Ouederni1, Ahmed Fadiel2,3, Nejla Stambouli1, Trudy J Scalize3, Hedi Ben Maiz4, Hafaona Kammoun Abid1, Rim Bouhaha1, Jose Sanchez-Corona5, Adel Hamza1,6*, Amel Benammar-Elgaaied1,*1Laboratory of Genetics, Immunology and Human Pathology ...
Thouraya Baroudi Ouederni, Ahmed Fadiel, Nejla Stambouli, et al   +3 more
doaj  

Evaluation of genetic diversity within different rabbit (Oryctolagus cuniculus) genotypes utilizing start codon targeted (SCoT) and inter-simple sequence repeat (ISSR) molecular markers [PDF]

Archives Animal Breeding
This work aimed at studying the genetic diversity among different rabbit genotypes reared in Egypt by two different molecular markers (start codon targeted, SCoT, and inter-simple sequence repeat, ISSR) to improve breeding strategies.
N. Elsayed, A. E. E. Mandour, M. K. A. Amin, F. M. Reda, H. S. A. Taha, A. Di Cerbo, M. M. Azzam, M. Alagawany   +7 more
doaj   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical applications, challenges, and future directions

Arthritis Care &Research, Accepted Article.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Genetic polymorphisms in sepsis

Pediatric Critical Care Medicine, 2005
Wide variability exists in the susceptibility to and outcome from sepsis even within similar intensive care unit populations. Some of this variability in the host may be due to genetic variation in genes coding for components of the innate immune response.To review the evidence for a genetic influence on the susceptibility to and outcome from sepsis ...
Mary K, Dahmer, Adrienne, Randolph, Sally, Vitali, Michael W, Quasney   +3 more
openaire   +3 more sources

Detection of genetic diversity among Indian strains of _Xanthomonas campestris_ pv. _mangiferaeindicae_ using PCR-RAPD [PDF]

, 2008
The randomly amplified polymorphic DNA (RAPD) technique was used to investigate the genetic diversity in 6 strains of _Xanthomonas campestris_ pv. _mangiferaeindicae_ (_Xcmi_), the causal pathogen of mango bacterial canker disease (MBCD).
Ram Kishun, Vijai Kumar Gupta
core   +1 more source

Detecting signatures of balancing selection to identify targets of anti-parasite immunity.

, 2010
Parasite antigen genes might evolve under frequency-dependent immune selection. The distinctive patterns of polymorphism that result can be detected using population genetic methods that test for signatures of balancing selection, allowing genes encoding
Conway, David J, Weedall, Gareth D
core   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez, Alejandro F. Manchón‐Gordón, Antonio Vidal‐Crespo, Rafael Caballero‐Flores, Jhon J. Ipus, Clara F. Conde   +5 more
wiley   +1 more source

Single Nucleotide Polymorphisms, Associated with Increased Risk of Irritable Bowel Syndrome with Predominant Constipation: A Meta Analysis

Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Introduction. Genetic predisposition in combination with environmental factors and the patient’s psychological and emotional state play a key role in the development of irritable bowel syndrome (IBS).
E. A. Trush, A. E. Karchevskaya, R. V. Maslennikov, E. A. Poluektova, O. S. Shifrin, V. T. Ivashkin   +5 more
doaj   +1 more source

Time‐Dependent Oxidation and Scale Evolution of a Wrought Co/Ni‐Based Superalloy

Advanced Engineering Materials, EarlyView.
This study shows how a new wrought Co/Ni‐based superalloy resists oxidation at 800 ∘$^\circ$C. The oxide scale changes from rough, fast‐growing spinel to a dense, protective chromia–alumina layer. Atom probe analysis reveals tiny refractory‐rich bubbles at the interface that mark the transition to long‐term, diffusion‐controlled protection ...
Cameron Crabb, Zachary T. Kloenne, Samuel R. Rogers, Chi Hang Dominik Kwok, Mark C. Hardy, Michele S. Conroy, David Dye   +6 more
wiley   +1 more source