Results 151 to 160 of about 349,199 (257)

Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes

open access: yesAdvanced Science, EarlyView.
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami   +15 more
wiley   +1 more source

Single‐Cell RNA Editing Identifies T Cell ADAR1 as a Key Regulator of Immune Exhaustion and Anti‐PD‐1 Resistance in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA editing analysis identifies ADAR1 as a regulator of dysfunctional T cell states in colorectal cancer. Elevated ADAR1 activity promotes T cell exhaustion and impairs antitumor immunity partly through TGF‐β‐SMAD signaling, contributing to anti‐PD‐1 resistance and highlighting T cell ADAR1 as a potential therapeutic target and biomarker ...
Da Kang   +10 more
wiley   +1 more source

An exciting Approach to Theoretical Spectroscopy

open access: yesAdvanced Science, EarlyView.
ABSTRACT Theoretical spectroscopy, and more generally, electronic‐structure theory, are powerful concepts for describing the complex many‐body interactions in materials. They cover methods from ground‐state properties to lattice excitations and light‐matter interaction, including time‐resolved variants.
Martí Raya‐Moreno   +29 more
wiley   +1 more source

Metabolomic adaptations and genetic polymorphism in ecopopulations of <i>Rhodiola linearifolia</i> Boriss. [PDF]

open access: yesFront Plant Sci
Yerbay M   +11 more
europepmc   +1 more source

CauFinder: Steering Cell‐State and Phenotype Transitions by Causal Disentanglement Learning

open access: yesAdvanced Science, EarlyView.
CauFinder combines causal disentanglement modeling and network control to prioritize causal drivers of cell‐state transitions from observational transcriptomic data. The framework separates transition‐relevant signals from spurious associations, nominates intervention targets across biological and disease contexts, and identifies DAAM1 as an actionable
Chengming Zhang   +11 more
wiley   +1 more source

Genetic polymorphism of circumsporozoite protein of Plasmodium falciparum isolates in children in Brazzaville, Republic of Congo. [PDF]

open access: yesMalar J
Baina MT   +8 more
europepmc   +1 more source

Growth‐Pathway‐Controlled van der Waals Epitaxy of Phase‐Selective Tin Sulfides

open access: yesAdvanced Science, EarlyView.
Growth‐pathway‐controlled van der Waals epitaxy enables deterministic phase selection and strain engineering in tin sulfide/WSe2 heterostructures. Direct growth of SnS induces substrate‐mediated strain and phase evolution, whereas sequential growth through an SnS2 buffer suppresses strain transfer and stabilizes pristine α‐SnS, revealing a versatile ...
Jaehyeok Lee   +2 more
wiley   +1 more source

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