Results 111 to 120 of about 329,928 (259)

Living with Risk, Aging with Uncertainty: A Narrative Review of Health and Genetic Vulnerability in Huntington’s Disease

open access: yesBiomedicines
Background/Objectives: Huntington’s disease (HD) is an autosomal dominant, neurodegenerative disorder that, because of the availability of presymptomatic genetic testing, places at-risk individuals in an anticipatory situation of great emotional, ethical,
Adriana V. Muñoz-Ortega   +2 more
doaj   +1 more source

Aspectos genéticos do transtorno obsessivo-compulsivo

open access: yesBrazilian Journal of Psychiatry, 2001
Since the first descriptions of obsessive-compulsive disorder (OCD), genetic factors have been implicated in the etiology of the illness. Twin studies show a high concordance rate for monozygotic twins.
Gonzalez Christina H
doaj  

Evolutionary biology and anthropology suggest biome reconstitution as a necessary approach toward dealing with immune disorders [PDF]

open access: yes, 2013
Industrialized society currently faces a wide range of non-infectious, immune-related pandemics. These pandemics include a variety of autoimmune, inflammatory and allergic diseases that are often associated with common environmental triggers and with ...
Adler   +133 more
core   +1 more source

Genetic predisposition to Behcet's disease mediated by a IL10RA enhancer polymorphism

open access: yesHeliyon
Background: Several studies suggested the genetic association between IL10RA variants and susceptibility to Behcet's disease (BD). However, the precise mechanism of the association is still unknown.
Handan Tan   +5 more
doaj   +1 more source

Frailty, genetic predisposition, and incident chronic kidney disease

open access: yesScientific Reports
Frailty is common among individuals with chronic kidney disease (CKD), whereas its impact on incident CKD risk remains unknown. This study aimed to prospectively evaluate the association between frailty and incident CKD risk, exploring the potential modification role of genetic risk factors (GRS).
Shanshan Zou   +9 more
openaire   +3 more sources

Genetics and Epigenetics of Arrhythmia and Heart Failure

open access: yesFrontiers in Genetics, 2013
Heart failure (HF) is the end stage of several pathological cardiac conditions including myocardial infarction, cardiac hypertrophy and hypertension. Various molecular and cellular mechanisms are involved in the development of HF. At the molecular level,
Burcu eDuygu   +2 more
doaj   +1 more source

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