Background/Objectives: Huntington’s disease (HD) is an autosomal dominant, neurodegenerative disorder that, because of the availability of presymptomatic genetic testing, places at-risk individuals in an anticipatory situation of great emotional, ethical,
Adriana V. Muñoz-Ortega +2 more
doaj +1 more source
Aspectos genéticos do transtorno obsessivo-compulsivo
Since the first descriptions of obsessive-compulsive disorder (OCD), genetic factors have been implicated in the etiology of the illness. Twin studies show a high concordance rate for monozygotic twins.
Gonzalez Christina H
doaj
Evolutionary biology and anthropology suggest biome reconstitution as a necessary approach toward dealing with immune disorders [PDF]
Industrialized society currently faces a wide range of non-infectious, immune-related pandemics. These pandemics include a variety of autoimmune, inflammatory and allergic diseases that are often associated with common environmental triggers and with ...
Adler +133 more
core +1 more source
Genetic predisposition to Behcet's disease mediated by a IL10RA enhancer polymorphism
Background: Several studies suggested the genetic association between IL10RA variants and susceptibility to Behcet's disease (BD). However, the precise mechanism of the association is still unknown.
Handan Tan +5 more
doaj +1 more source
Frailty, genetic predisposition, and incident chronic kidney disease
Frailty is common among individuals with chronic kidney disease (CKD), whereas its impact on incident CKD risk remains unknown. This study aimed to prospectively evaluate the association between frailty and incident CKD risk, exploring the potential modification role of genetic risk factors (GRS).
Shanshan Zou +9 more
openaire +3 more sources
Genetically selected baby free of inherited predisposition to early-onset Alzheimer's disease [PDF]
Merle Spriggs
openalex +1 more source
Genetics and Epigenetics of Arrhythmia and Heart Failure
Heart failure (HF) is the end stage of several pathological cardiac conditions including myocardial infarction, cardiac hypertrophy and hypertension. Various molecular and cellular mechanisms are involved in the development of HF. At the molecular level,
Burcu eDuygu +2 more
doaj +1 more source
Association between SNCA Intron and genetic predisposition to sporadic Parkinson's disease: a meta-analysis based on 49576 individuals [PDF]
Peng Li +4 more
openalex +1 more source
Genetic Bases for Predisposition to Common Multifactorial Disease in Man. Part II [PDF]
Rumena Petkova +2 more
openalex +1 more source
Genetic variability shapes the alternative pathway complement activity and predisposition to complement‐related diseases [PDF]
Santiago Rodrı́guez de Córdoba
openalex +1 more source

