Results 111 to 120 of about 319,093 (308)

GENETIC FACTORS AND PREDISPOSITION TO DISEASE

This article reviews genetic factors that influence susceptibility to various diseases, including both hereditary and multifactorial disorders. The study relies on the analysis of existing data and the results of meta-analyses to substantiate the significance of genetic predisposition in disease pathogenesis.
Karimov Abduhalim Abdurozikovich, Hamidova Zebiniso Hikmatovna   +1 more
openaire   +2 more sources

Genetic predisposition to Parkinson's disease: CYP2D6 and HFE in the Faroe Islands

Pharmacogenetics and Genomics, 2008
To investigate whether the genetic variants of CYP2D6 and HFE are more frequent in Parkinson's disease (PD) patients compared with controls in a population where the prevalence of these variants and PD are increased.Blood samples were collected from 79 PD patients and 154 controls in the Faroe Islands.
Halling, Jónrit, Petersen, Maria Skaalum, Grandjean, Philippe, Weihe, Pál, Brøsen, Kim   +4 more
openaire   +3 more sources

Vat Polymerization 3D Printing for Controlled Drug Release Applications

Advanced Materials Technologies, EarlyView.
ABSTRACT Vat polymerization (VP) 3D printing, a light‐based additive manufacturing technique, has emerged as a promising technique for fabricating complex drug delivery systems with high precision and spatial resolution. This layer‐by‐layer manufacturing process enables the creation of intricate geometries and customizable architectures, which are ...
Hafiz Busari, O. Thompson Mefford, M. Aaron Vaughn   +2 more
wiley   +1 more source

Genome-wide analysis of genetic predisposition to Alzheimer’s disease and related sex disparities

Alzheimer’s Research & Therapy, 2019
Background Alzheimer’s disease (AD) is the most common cause of dementia in the elderly and the sixth leading cause of death in the United States. AD is mainly considered a complex disorder with polygenic inheritance.
Alireza Nazarian, Anatoliy I. Yashin, Alexander M. Kulminski   +2 more
doaj   +1 more source

Chemically Doped Conductive Polymers for Wearable Health Monitoring

Advanced Materials Technologies, EarlyView.
Among conductive polymers, poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS), polyaniline (PANI), and polypyrrole (PPy) are the most studied and applied. Chemical doping significantly boosts intrinsic conductivity and mechanical robustness.
Mengdi Zuo, Jian Song, Hong Hu, Le Zheng, Lei Zhang, Charles H. Lawrie   +5 more
wiley   +1 more source

CHARACTERISTICS OF INDIVIDUALS UNDERGOING PANEL GENETIC TESTING FOR PRIMARY BRAIN TUMORS [PDF]

, 2018
Background. Currently, there are no genetic testing guidelines for patients with a primary brain tumor (PBT). This population is largely understudied in terms of the family history, tumor grade, pathology, and their relation to genetic contribution.
Azam, Sarah
core   +1 more source

Fabric‐Based Wearable Robotic Exoskeleton Gloves: Advancements and Challenges

Advanced Materials Technologies, EarlyView.
This review highlights interdisciplinary technological advances in fabric‐based robotic gloves, focusing on progress in design, fabrication, actuation, sensing, control, and power and energy requirements. It also addresses performance testing and validation, including biomechanical, strength, functional, user experience, and durability assessments, to ...
Ayse Feyza Yilmaz, Gökhan Ince, Ozgur Atalay   +2 more
wiley   +1 more source

Physical activity, genetic predisposition, and incident cardiovascular disease: Prospective analyses of the UK Biobank

Journal of Sport and Health Science
Background: It is unclear whether physical activity can benefit participants with high genetic predisposition to cardiovascular disease. We examined the joint associations of intensity-specific physical activity and genetic predisposition (based on ...
Matthew N. Ahmadi, Hamish D. Mundell, Greg T. Sutherland, Mark Hamer, Elina Sillanpää, Joanna M. Blodgett, Borja del Pozo Cruz, Emmanuel Stamatakis   +7 more
doaj   +1 more source

Conformable Microelectrode Arrays Integrated with a Scoop‐Shaped Slide‐Well for Dynamic Electrophysiological Profiling of Patient‐Derived Cardiac Organoids

Advanced Science, EarlyView.
A flexible, ultrathin multi‐channel microelectrode array (MEA) conformally integrated onto a curved slide‐well enables stable electrical interfacing with 3D cardiac organoids. The geometry‐guided self‐alignment allows simultaneous recording of extracellular field potentials and contractile motion from irregular, beating tissues.
Ye Seul Kim, Jeonghwa Jeong, Gyeonghwa Heo, Young Woo Kwon, Jeongha Lee, Yoon Ji Jeong, Gyu Tae Park, Seongdo Jeong, Ki Won Hwang, Murim Choi, Jinhong Shin, Suck Won Hong, Jae Ho Kim   +12 more
wiley   +1 more source

Outcomes of Genetic Testing in a Genitourinary Genetics Clinic [PDF]

, 2018
Several known hereditary cancer syndromes confer an increased risk for genitourinary (GU)related malignancies. Various guidelines indicate when to refer patients to genetic counseling for GU-related hereditary cancer syndromes but there is limited ...
Pace, Annelise
core   +1 more source