Results 131 to 140 of about 284,664 (210)

Global trends and epidemiological shifts in gastrointestinal cancers: insights from the past four decades

Cancer Communications, EarlyView.
Abstract Background The epidemiological profiles of gastrointestinal (GI) cancers vary across countries and over time, largely reflecting variations in risk factors and screening practices. We aimed to provide an overview of the current global burden of the five major types of GI cancers and conduct an updated evaluation of the long‐term trends of GI ...
Mengmeng Li, Sumei Cao, Rui‐Hua Xu
wiley   +1 more source

Genetic Determinants of Colonic Diverticulosis-A Systematic Review. [PDF]

Genes (Basel)
Nehring P, Przybyłkowski A.
europepmc   +1 more source

A polygenic score for height identifies an unmeasured genetic predisposition among pediatric patients with idiopathic short stature. [PDF]

Genome Med
Shelley JP, Shi M, Peterson JF, Van Driest SL, Simmons JH, Mosley JD.   +5 more
europepmc   +1 more source

Phytochemicals in Cancer Therapy: A Structured Review of Mechanisms, Challenges, and Progress in Personalized Treatment

Chemistry &Biodiversity, Accepted Article.
Objective: Cancer remains a global health challenge, necessitating new therapeutic options. Phytochemicals, with diverse chemical structures and biological activities, show promise as anticancer agents. This review explores key phytochemicals, their mechanisms, and their potential integration into cancer therapy.
Alaa A. A. Aljabali, Mohammad A. Obeid, Rasha M. Bashatwah, Esam Qnais, Omar Gammoh, Abdelrahim Alqudah, Vijay Mishra, Yachana Mishra, Mohammad Ahmed Khan, Suhel Parvez, Mohamed El-Tanani, Taher Hatahet   +11 more
wiley   +1 more source

Dietary inflammatory potential, genetic predisposition, and incidence of Crohn's disease and ulcerative colitis. [PDF]

Nutr Metab (Lond)
Gu JM, Zhao M, Zhu J, Tao HW, Shao XP, Qin LQ, Ge YY, Chen GC.   +7 more
europepmc   +1 more source

Contemporary Perspectives on Chronic Renal Disorders

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok, Poornima Ajay Manjrekar, Bhushan C. Shetty, Sujina S. S, Rukmini Mysore Srikantiah, Sowndarya Kollampare   +5 more
wiley   +1 more source

Fisetin as a Blueprint for Senotherapeutic Agents – Elucidating Geroprotective and Senolytic Properties with Molecular Modeling

Chemistry – A European Journal, Volume 31, Issue 16, March 17, 2025.
The exceptional senotherapeutic activity of fisetin, combining both geroprotective and senolytic effects, was validated using computational chemistry tools, establishing it as a cornerstone template for the development of novel agents. Abstract Targeting senescent cells and the factors that accelerate this pathological state has recently emerged as a ...
Maciej Spiegel
wiley   +1 more source

Possible familial predisposition in superior mesenteric artery syndrome with surgical management: A case report. [PDF]

Medicine (Baltimore)
Maraqah M, Al Tamimi MF, Abu Aram S, Hmedat S, Abueisha M, Hmeedat Y.   +5 more
europepmc   +1 more source

Hallmarks of Neuroblastoma—Pathophysiology, Diagnosis, and Therapeutic Interventions

Cancer Nexus, EarlyView.
ABSTRACT Neuroblastoma, the most common extracranial solid tumor in childhood, continues to challenge clinicians and researchers because of its heterogeneous nature and complex pathophysiology. Recent breakthroughs in molecular profiling revealed intricate genetic alterations driving tumor progression, necessitating an updated perspective on the ...
Abhimanyu Thakur, Anne Dijkstra
wiley   +1 more source

Associations Between Physical Capability Markers and Risk of Coronary Artery Disease: A Prospective Study of 439,295 UK Biobank Participants. [PDF]

Healthcare (Basel)
Liu D, Yang C, Guo T, Guo Y, Xiong J, Chen R, Deng S.   +6 more
europepmc   +1 more source