Results 111 to 120 of about 116,877 (316)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Genetic programming in data mining for drug discovery

open access: yes, 2004
Genetic programming (GP) is used to extract from rat oral bioavailability (OB) measurements simple, interpretable and predictive QSAR models which both generalise to rats and to marketed drugs in humans. Receiver Operating Characteristics (ROC) curves
Barrett, S.J., Langdon, W.B.
core  

基于遗传-二次规划法的封闭差动人字齿轮传动系统混合优化设计

open access: yesJixie chuandong, 2014
Using the positive transmission way of modified gear,a mathematical optimization model of the encased differential herringbone gear transmission system is set up by taking the lightest gear weight of this transmission system as the optimization objective.
朱增宝, 朱如鹏, 尹敏
doaj  

Design of Finite Impulse Response Filters Based on Genetic Algorithm

open access: yesDiyala Journal of Engineering Sciences, 2013
Genetic Algorithms (GAs) are used to solve many optimization problems in science and engineering such as pattern recognition, robotics, biology, medicine, and many other applications.
Raaed Faleh Hassan, Ali Subhi Abbood
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Genetic programming and deductive-inductive learning: a multistrategy approach [PDF]

open access: yes, 1998
Proceedings of: 15th International Conference on Machine Learning, Madison (Wisconsin, USA), July 24-27, 1998.Genetic Programming (GP) is a machine learning technique that was not conceived to use domain knowledge for generating new candidate solutions ...
Borrajo, Daniel   +5 more
core  

Finding state-of-the-art non-cryptographic hashes with genetic programming [PDF]

open access: yes, 2006
Proceding of: 9th International Conference, Reykjavik, Iceland, September 9-13, 2006.The design of non-cryptographic hash functions by means of evolutionary computation is a relatively new and unexplored problem.
Ribagorda Garnacho, Arturo   +10 more
core   +1 more source

Daily rainfall interpolation models obtained by means of genetic programming

open access: yesRevista Facultad de Ingeniería Universidad de Antioquia, 2015
The evolutionary computing algorithm of genetic programming was applied to obtain mathematical daily rainfall interpolation models in one climatologic station, using the measured data in nearby stations in Cutzamala River basin in Mexico.
Maritza Liliana Arganis-Juárez   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Genetic Programming Approach to Geometrical Digital Content Modeling in Web Oriented Applications [PDF]

open access: yes
The paper presents the advantages of using genetic techniques in web oriented problems. The specific area of genetic programming applications that paper approaches is content modeling.
Dragos PALAGHITA
core  

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