Results 91 to 100 of about 9,566,413 (315)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Accurate High Performance Concrete Prediction with an Alignment-Based Genetic Programming System
International Journal of Concrete Structures and Materials, 2018 In 2013, our research group published a contribution in which a new version of genetic programming, called Geometric Semantic Genetic Programming (GSGP), was fostered as an appropriate computational intelligence method for predicting the strength of high-
Leonardo Vanneschi +3 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Genetic Programming for Object Detection: A Two-Phase Approach with an Improved Fitness Function
ELCVIA Electronic Letters on Computer Vision and Image Analysis, 2007 This paper describes two innovations that improve the efficiency and effectiveness of a genetic programming approach to object detection problems. The approach uses genetic programming to construct object detection programs that are applied, in a moving ...
Mengjie Zhang, Urvesh Bhowan, Bunna Ny
doaj +1 more source
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Applications of Genetic Programming in Cancer [PDF]
Middle East Journal of CancerArtificial intelligence (AI) and machine learning (ML) methods have gained notable recognition for their innovative problem-solving approaches, which notably do not require understanding the problem’s physical underpinnings.
Hamid Reza Niazkar +4 more
doaj
Using Rapid Chlorophyll Fluorescence Transients to Classify Vitis Genotypes
Plants, 2020 When a dark-adapted leaf is illuminated with saturating light, a fast polyphasic rise of fluorescence emission (Kautsky effect) is observed. The shape of the curve is dependent on the molecular organization of the photochemical apparatus, which in turn ...
Jorge Marques da Silva +6 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Finding Solutions to Sudoku Puzzles Using Human Intuitive Heuristics
South African Computer Journal, 2012 Sudoku is a logical puzzle that has achieved international popularity. Given this, there have been a number of computer solvers developed for this puzzle. Various methods including genetic algorithms, simulated annealing, particle swarm optimization and
Nelishia Pillay
doaj