Results 81 to 90 of about 3,372,146 (369)
Enhanced recombination empowers the detection and mapping of Quantitative Trait Loci
Communications BiologyModern plant breeding, such as genomic selection and gene editing, is based on the knowledge of the genetic architecture of desired traits. Quantitative trait loci (QTL) analysis, which combines high throughput phenotyping and genotyping of segregating ...
Laia Capilla-Pérez +8 more
doaj +1 more source
Pathogens, 2022 Genetic recombination is used as a tool for modifying the composition of poxvirus genomes in both discovery and applied research. This review documents the history behind the development of these tools as well as what has been learned about the processes
David Hugh Evans
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Optimal Recombination in Genetic Algorithms [PDF]
, 2013 This paper surveys results on complexity of the optimal recombination problem (ORP), which consists in finding the best possible offspring as a result of a recombination operator in a genetic algorithm, given two parent solutions.
Eremeev, Anton V., Kovalenko, Julia V.
core
High fidelity of RecA-catalyzed recombination: a watchdog of genetic diversity [PDF]
, 2006 Homologous recombination plays a key role in generating genetic diversity, while maintaining protein functionality. The mechanisms by which RecA enables a single-stranded segment of DNA to recognize a homologous tract within a whole genome are poorly ...
Sagi, Dror, Stavans, Joel, Tlusty, Tsvi
core +6 more sources
Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
Recombination in Enteroviruses, a Multi-Step Modular Evolutionary Process
Viruses, 2019 RNA recombination is a major driving force in the evolution and genetic architecture shaping of enteroviruses. In particular, intertypic recombination is implicated in the emergence of most pathogenic circulating vaccine-derived polioviruses, which have ...
Claire Muslin +4 more
doaj +1 more source
Viruses, 2023 Bunyamwera virus is the prototype of the Bunyamwera serogroup, which belongs to the order Bunyavirales of the Orthobunyavirus genus in the Peribunyaviridae family. Bunyamwera is a negative-sense RNA virus composed of three segments S, M, and L.
Moufid Mhamadi +11 more
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Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Frontiers in Cellular and Infection Microbiology, 2023 Co-circulation of different human immunodeficiency virus type 1 HIV-1 subtypes among infected populations can lead to the generation of new recombinants. In Pakistan, subtype A1 and CRF02_AG are the dominant strains circulating among key populations. The
Abdur Rashid +10 more
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On the Nature of Poliovirus Genetic Recombinants
Journal of General Virology, 1974 Summary Recombinant and parental poliovirus particles were indistinguishable by ratezonal and isopycnic sedimentation, and by u.v. inactivation. Sensitive selective procedures, applied to ts + recombinants to detect genetic segregation of one parent, failed to reveal any.
D. Delong +3 more
openaire +2 more sources