Results 81 to 90 of about 213,537 (298)
Complete genome sequences of two feline Leukemia virus subgroup B isolates with novel recombination sites [PDF]
, 2013 It is generally accepted that all primary isolates of feline leukemia virus (FeLV) contain a subgroup A virus (FeLV-A) that is essential for transmission.
Bae +12 more
core +1 more source
Detecting Genetic Recombination
, 2008 Recombination is the major motor of evolution. While mutations result in gradual changes, recombination reshuffles entire functional modules and thus progresses evolution in leaps and bounds. We need to identify recombination breakpoints in sequences to understand the evolutionary process, the impact of recombination, and to reconstruct the ...
openaire +4 more sources
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
Genetic recombination is targeted towards gene promoter regions in dogs
, 2013 The identification of the H3K4 trimethylase, PRDM9, as the gene responsible for recombination hotspot localization has provided considerable insight into the mechanisms by which recombination is initiated in mammals.
Adam Auton +12 more
core +2 more sources
Genetic characterization of Pepino mosaic virus isolates from Belgian greenhouse tomatoes reveals genetic recombination [PDF]
, 2008 Over a period of a few years, Pepino mosaic virus (PepMV) has become one of the most important viral diseases in tomato production worldwide. Infection by PepMV can cause a broad range of symptoms on tomato plants, often leading to significant financial ...
Bragard, C. +7 more
core +3 more sources
Indirect stimulation of genetic recombination [PDF]
Proceedings of the National Academy of Sciences, 1983 Recombination between lac Z alleles in crosses of λ lac Z 1 - × λ lac Z 2 - and F - lac Z 1 - × λ lac
K. Brooks Low, Efim I. Golub
openaire +3 more sources
Molecular Oncology, EarlyView.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
wiley +1 more source
Measuring Homologous Recombination Rates between Chromosomal Locations in Salmonella
Bio-Protocol, 2019 Homologous recombination between two similar DNA molecules, plays an important role in the repair of double-stranded DNA breaks. Recombination can occur between two sister chromosomes, or between two locations of similar sequence identity within the same
Gerrit Brandis +2 more
doaj +1 more source
Smc5/6 is required for repair at collapsed replication forks. [PDF]
, 2006 In eukaryotes, three pairs of structural-maintenance-of-chromosome (SMC) proteins are found in conserved multisubunit protein complexes required for chromosomal organization.
Ampatzidou, Eleni +3 more
core +3 more sources
Molecular Oncology, EarlyView.In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen +17 more
wiley +1 more source