Results 121 to 130 of about 5,434,712 (302)

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Targeting Inhibin Enhances Wagyu Oocyte Competence and Embryo Quality: A Comparative Study of In Vivo Immunization and In Vitro Antibody Supplementation

Antioxidants
High-efficiency Ovum Pick-Up (OPU) and in vitro embryo production (IVP) are critical for the genetic improvement of high-value Wagyu cattle. However, oxidative stress and mitochondrial dysfunction during oocyte maturation remain major bottlenecks ...
Jingyu Ren, Fuhan Liu, Gang Liu, Biao Wang, Jie Zhu, Yongbin Liu, Yanfeng Dai   +6 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Genetic regulation of Corynebacterium glutamicum metabolism

, 2006
Wendisch VF. Genetic regulation of Corynebacterium glutamicum metabolism. Journal of Microbiology and Biotechnology. 2006;16(7):999-1009.Physiological, biochemical and genetic studies of Corynebacterium glutamicum, a workhorse of white biotechnology used
Wendisch, Volker F. ; https://orcid.org/
core  

A genetic approach for synthesizing metabolic models from time series

, 2012
In this paper we introduce a new approach, based on genetic algorithms and multiple linear regression, for the synthesis of flux regulation functions in metabolic models from observed time series.
MANCA, Vincenzo, Vincenzo Manca, Alberto Castellini, CASTELLINI, ALBERTO, BUSATO, MIRKO, Mauro Zucchelli, Mirko Busato, Zucchelli, Mauro   +7 more
core   +1 more source

Plasmid-encoded phosphatase RapP enhances cell growth in non-domesticated Bacillus subtilis strains

Nature Communications
The trade-off between rapid growth and other important physiological traits (e.g., survival and adaptability) poses a fundamental challenge for microbes to achieve fitness maximization. Studies on Bacillus subtilis biology often use strains derived after
Manlu Zhu, Yiheng Wang, Haoyan Mu, Fei Han, Qian Wang, Yongfu Pei, Xin Wang, Xiongfeng Dai   +7 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Genetic variant for behavioral regulation factor of executive function and its possible brain mechanism in attention deficit hyperactivity disorder

, 2018
As a childhood-onset psychiatric disorder, attention deficit hyperactivity disorder (ADHD) is complicated by phenotypic and genetic heterogeneity. Lifelong executive function deficits in ADHD are described in many literatures and have been proposed as ...
Wu, Zhaomin, Suhua Chang, Ying Qian, Binrang Yang, Yufeng Wang, Qingjiu Cao, Yang, Li, Cao, Qingjiu, Yong Liu, Xiao Sun, Qian, Ying, Wang, Yufeng, Zhaomin Wu, Li Yang, Sun, Xiao, Yang, Binrang, Chang, Suhua, Liu, Yong   +17 more
core   +1 more source

Role of Glutathione in Alleviating Chilling Injury in Bovine Blastocysts: Mitochondrial Restoration and Apoptosis Inhibition

Antioxidants
Short-term hypothermic storage at 4 °C represents a promising non-freezing alternative for transporting bovine embryos and synchronizing assisted reproductive procedures.
Jingyu Ren, Fuhan Liu, Gang Liu, Biao Wang, Jie Zhu, Yongbin Liu, Yanfeng Dai   +6 more
doaj   +1 more source