Results 51 to 60 of about 681,929 (290)

History and current status of plant genetic resources conserved and maintained by the Hungarian central genebank

open access: yesGenetic Resources
The predecessor of the National Centre for Biodiversity and Gene Conservation (NBGK) was established in Hungary in 1959. The 1950s were hectic times for Hungarian plant breeders, and many new genetic materials were registered in the National List of ...
Zoltan Ay   +5 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Collecting Mediterranean wild species of the Brassica oleracea group (Brassica sect. Brassica)

open access: yesGenetic Resources
Within the framework of the project EUBRASWILD (Capturing Brassica Wild Relatives Diversity in Southeastern Europe), several collecting missions were organized, targeting wild Brassica complex species (2n = 18), belonging to the gene pool of Brassica ...
Lorenzo Maggioni   +6 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

History and future of industrial crop accessions preserved by CREA-CI in Bologna and Rovigo, Italy

open access: yesGenetic Resources
The conservation and exploitation of industrial crops at the Cereal and Industrial Crop Centre of the Council for Research in Agriculture and Economics (CREA-CI, the Bologna and Rovigo Research Centres) date back to the beginning of the 20th century and
Ilaria Alberti   +5 more
doaj   +1 more source

The state of conservation of animal genetic resources in Slovakia

open access: yesGenetic Resources, 2022
To effectively conserve animal genetic resources, countries need to periodically review their conservation efforts and reflect on actual problems and challenges.
Ján Tomka, Ján Huba, Ivan Pavlík
doaj  

Potential of Wild Relatives of Wheat: Ideal Genetic Resources for Future Breeding Programs [PDF]

open access: gold, 2021
Alireza Pour‐Aboughadareh   +3 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Organization of plant Biological Resource Centers for research in France: History, evolution and current status

open access: yesGenetic Resources
Since their inception, the French academic organizations dedicated to agricultural research have developed plant collections in genebanks, often within a public–private framework, to support the study of plant traits and the development of new improved ...
Valerie Bergheaud   +19 more
doaj   +1 more source

Home - About - Disclaimer - Privacy