Results 21 to 30 of about 8,942,317 (309)

Attitude toward genetic testing for cancer risk in Istanbul

, 2004
To identify attitudes toward genetic testing, and the effects of this information on decisions regarding issues such as pregnancy, abortion, and prophylactic surgery, several subsets of the Turkish Population were surveyed in hospital settings ...
BASARAN, Gülcan, TOPAL, A, ALIUSTAOGLU, M, GUMUS, Müjde Dila, TURHAL, NS, Ekenel, MELTEM, YUMUK, PF   +6 more
core   +3 more sources

Urinary exosome miR-146a is a potential marker of albuminuria in essential hypertension

Journal of Translational Medicine, 2018
Background There is increasing interest in using extracellular vesicle-derived microRNAs (miRNAs) as biomarkers in renal dysfunction and injury. Preliminary evidence indicates that miRNAs regulate the progression of glomerular disease.
Javier Perez-Hernandez, Dolores Olivares, Maria J. Forner, Ana Ortega, Elena Solaz, Fernando Martinez, Felipe J. Chaves, Josep Redon, Raquel Cortes   +8 more
doaj   +1 more source

Looking at Intergenerational Risk Factors in Schizophrenia Spectrum Disorders: New Frontiers for Early Vulnerability Identification?

Frontiers in Psychiatry, 2020
Offspring of individuals with serious mental illness (SMI) constitute a special population with a higher risk of developing psychiatric disorders, which is also highly prevalent among referrals to child and adolescent mental health services (CAMHS). They
Michele Poletti, Eva Gebhardt, Lorenzo Pelizza, Antonio Preti, Andrea Raballo, Andrea Raballo   +5 more
doaj   +1 more source

A survey of genome-wide association studies, polygenic scores and UK Biobank highlights resources for autoimmune disease genetics

Frontiers in Immunology, 2022
Autoimmune diseases share a general mechanism of auto-antigens harming tissues. Still. they are phenotypically diverse, with genetic as well as environmental factors contributing to their etiology at varying degrees.
Rochi Saurabh, Césaire J. K. Fouodo, Inke R. König, Hauke Busch, Inken Wohlers   +4 more
doaj   +1 more source

Genetics: Relative risk [PDF]

Nature, 2015
Mutations in BRCA genes predispose women to cancer, but outside influences shape the ultimate risk.
openaire   +2 more sources

Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders [PDF]

, 2018
Background There is increasing evidence for shared genetic susceptibility between schizophrenia and bipolar disorder. Although genetic variants only convey subtle increases in risk individually, their combination into a polygenic risk score constitutes a
Lin, K., Rujescu, D., Os, J. V., Walshe, Muriel, Kahn, R, McIntosh, AM, Vassos, E., Picchioni, M., Toulopoulou, Timothea, Ranlund, S, Thygesen, J. H., Iyegbe, Conrad, Crespo-Facorro, B, Calafato, MS, Calafato, Maria Stella, Vassos, E, Kravariti, Eugenia, Walshe, M, Di Forti, Marta, Picchioni, Marco, Di Forti, M, Diez-Revuelta, Alvaro, Os, Jim van, Kahn, R., Lewis, CM, Thygesen, Johan H., Jablensky, A, Lewis, Cathryn M., Powell, J, McDonald, Colm, Iyegbe, C., McIntosh, Andrew M., McQuillin, A, McQuillin, A., Psychosis Endophenotypes International Consortium (PEIC), Kahn, Rene, Hall, M-H, Iyegbe, C, Kalaydjieva, L, McDonald, C., Cahn, W, Crespo-Facorro, B., Kalaydjieva, L., Hall, M. -H., Hall, Mei-Hua, Zartaloudi, E., Vassos, Evangelos, Rujescu, Dan, Bramon, E, Bramon, Elvira, Murray, RM, Toulopoulou, T, Forti, Marta Di, Murray, Robin M., Jablensky, Assen, Picchioni, M, Murray, R. M., McDonald, C, Calafato, M. S., Forti, M. D., Thygesen, JH, Lewis, C. M., Jablensky, A., Van Os, Jim, Powell, John, Rujescu, D, Lin, Kuang, Shaikh, M., ?, ?, Crespo-Facorro, Benedicto, Genetic Risk and Outcome of Psychosis (GROUP) consortium, Bramon, E., Shaikh, M, Crespo Facorro, Benedicto, Kravariti, E, Kravariti, E., Shaikh, Madiha, Walshe, M., McQuillin, Andrew, Zartaloudi, E, Ranlund, S., Díez-Revuelta, Á, Zartaloudi, Eirini, Genetic Risk and Outcome of Psychosis (GROUP) consortium, Kalaydjieva, Luba, Ranlund, Siri, Cahn, Wiepke, McIntosh, A. M., Cahn, W., Lin, K, Os, JV, Powell, J., Díez-Revuelta, A., Brain, Onderzoeksgroep 11, Onderzoek   +95 more
core   +1 more source

Translating principles of precision medicine into speech-language pathology: Clinical trial of a proactive speech and language intervention for infants with classic galactosemia

HGG Advances, 2022
Summary: Precision medicine is an emerging approach to managing disease by taking into consideration an individual’s genetic and environmental profile toward two avenues to improved outcomes: prevention and personalized treatments.
Beate Peter, Jennifer Davis, Lizbeth Finestack, Carol Stoel-Gammon, Mark VanDam, Laurel Bruce, Yookyung Kim, Linda Eng, Sarah Cotter, Emily Landis, Sam Beames, Nancy Scherer, Ina Knerr, Delaney Williams, Claire Schrock, Nancy Potter   +15 more
doaj   +1 more source

Chromosome 1p13 genetic variants antagonize the risk of myocardial infarction associated with high ApoB serum levels [PDF]

, 2012
Background Genetic variation at 1p13 modulates serum lipid levels and the risk of coronary heart disease through the regulation of serum lipid levels. Here we investigate if the interaction between genetic variants at 1p13 and serum lipid levels affects ...
Gigante, B, Vikström Max, Ulf de Faire, Ye, S, Max Vikström, Bruna Gigante, Ye Shu, de Faire, U, Gigante Bruna, Leander Karin, Karin Leander, Leander, K, de Faire Ulf, Vikstrom, M, Shu Ye, Gigante, B,, Leander, K,, de, Faire U,   +17 more
core   +2 more sources

Identification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in South Africa [PDF]

, 2013
Includes abstract.Includes bibliographical references.Oesophageal squamous cell carcinoma (OSCC) is a complex disease, determined by the interaction of genetic factors with environmental risk factors. In South Africa, OSCC is a major malignancy occurring
Matejcic, Marco
core   +1 more source

A Polygenic Score for Type 2 Diabetes Improves Risk Stratification Beyond Current Clinical Screening Factors in an Ancestrally Diverse Sample

Frontiers in Genetics, 2022
A substantial proportion of the adult United States population with type 2 diabetes (T2D) are undiagnosed, calling into question the comprehensiveness of current screening practices, which primarily rely on age, family history, and body mass index (BMI).
James R. Ashenhurst, Olga V. Sazonova, Olivia Svrchek, Stacey Detweiler, Ryosuke Kita, Liz Babalola, Matthew McIntyre, Stella Aslibekyan, Pierre Fontanillas, Suyash Shringarpure, 23andMe Research Team, Jeffrey D. Pollard, Bertram L. Koelsch   +12 more
doaj   +1 more source