Results 51 to 60 of about 8,942,317 (309)

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo   +9 more
wiley   +1 more source

Adjusting the frequency of mammography screening on the basis of genetic risk: Attitudes among women in the UK. [PDF]

open access: yes, 2015
Purpose To explore public attitudes towards modifying frequency of mammography screening based on genetic risk. Methods Home-based interviews were carried out with a population-based sample of 942 women aged 18–74 years in the UK.
Side, L   +7 more
core  

Genetic risk and value

open access: yes, 2018
A conceptual truth about risks is that they involve a possible and future adverse effect or a negative value of some kind. The genetic risks that individuals may face in the health care setting differ in some crucial respects to other kind of risks.
Kihlbom, Ulrik,
core   +1 more source

Genetic markers of obesity risk: stronger associations with body composition in overweight compared to normal-weight children. [PDF]

open access: yes, 2011
Genetic factors are important determinants of overweight. We examined whether there are differential effect sizes depending on children's body composition.
Kries, Rüdiger von   +17 more
core   +1 more source

Familial Genetic Risk

open access: yesAMA Journal of Ethics, 2005
A physician outlines the concept of the family covenant, an agreement between consenting family members that defines exactly how and when medical information is divulged to other family members. Virtual Mentor is a monthly bioethics journal published by the American Medical Association.
openaire   +2 more sources

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine   +17 more
wiley   +1 more source

Clinical Aspects of Genetic and Non-Genetic Cardiovascular Risk Factors in Familial Hypercholesterolemia

open access: yes, 2022
Familial hypercholesterolemia (FH) is the most common monogenic metabolic disorder characterized by considerably elevated low-density lipoprotein cholesterol (LDL-C) levels leading to enhanced atherogenesis, early cardiovascular disease (CVD), and ...
Noémi Zsíros   +13 more
core   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz   +12 more
wiley   +1 more source

Brain structural alterations, genetic risk variants and the onset of psychosis [PDF]

open access: yes, 2015
One of the central motivations behind research of the at-risk mental state is to prevent or delay potential transition to psychosis and further progression to schizophrenia, by studying the early signs and symptoms without potential confounding effects ...
Harrisberger, Fabienne
core   +1 more source

Cancer prognosis and treatment results in patients with PTEN Hamartoma Tumour Syndrome (PHTS)—a European cohort study

open access: yesBJC Reports
Background PTEN hamartoma tumour syndrome (PHTS) patients have a high hereditary risk of cancer, especially breast (BC), endometrial (EC), and thyroid cancer (TC). However, the prognosis of PHTS-related cancers is unknown.
Linda A. J. Hendricks   +49 more
doaj   +1 more source

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