Results 51 to 60 of about 8,942,317 (309)
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo +9 more
wiley +1 more source
Adjusting the frequency of mammography screening on the basis of genetic risk: Attitudes among women in the UK. [PDF]
Purpose To explore public attitudes towards modifying frequency of mammography screening based on genetic risk. Methods Home-based interviews were carried out with a population-based sample of 942 women aged 18–74 years in the UK.
Side, L +7 more
core
A conceptual truth about risks is that they involve a possible and future adverse effect or a negative value of some kind. The genetic risks that individuals may face in the health care setting differ in some crucial respects to other kind of risks.
Kihlbom, Ulrik,
core +1 more source
Genetic markers of obesity risk: stronger associations with body composition in overweight compared to normal-weight children. [PDF]
Genetic factors are important determinants of overweight. We examined whether there are differential effect sizes depending on children's body composition.
Kries, Rüdiger von +17 more
core +1 more source
A physician outlines the concept of the family covenant, an agreement between consenting family members that defines exactly how and when medical information is divulged to other family members. Virtual Mentor is a monthly bioethics journal published by the American Medical Association.
openaire +2 more sources
Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine +17 more
wiley +1 more source
Familial hypercholesterolemia (FH) is the most common monogenic metabolic disorder characterized by considerably elevated low-density lipoprotein cholesterol (LDL-C) levels leading to enhanced atherogenesis, early cardiovascular disease (CVD), and ...
Noémi Zsíros +13 more
core +1 more source
Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz +12 more
wiley +1 more source
Brain structural alterations, genetic risk variants and the onset of psychosis [PDF]
One of the central motivations behind research of the at-risk mental state is to prevent or delay potential transition to psychosis and further progression to schizophrenia, by studying the early signs and symptoms without potential confounding effects ...
Harrisberger, Fabienne
core +1 more source
Background PTEN hamartoma tumour syndrome (PHTS) patients have a high hereditary risk of cancer, especially breast (BC), endometrial (EC), and thyroid cancer (TC). However, the prognosis of PHTS-related cancers is unknown.
Linda A. J. Hendricks +49 more
doaj +1 more source

