Results 171 to 180 of about 5,319,582 (307)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Bidirectional genetic selection of behaviors involved in social interaction of Wistar rats. [PDF]

Braz J Med Biol Res, 2022
Bonuti R, Morato S.
europepmc   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Chicken white egg chemerin as a tool for genetic selection for egg weight and hen fertility. [PDF]

Front Physiol, 2022
Bernardi O, Reverchon M, Estienne A, Baumard Y, Ramé C, Brossaud A, Combarnous Y, Froment P, Dupont J.   +8 more
europepmc   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Multi-Year Phenotypic Assessment and Genetic Selection in Progeny Trials of <i>Liriodendron</i> Hybrids. [PDF]

Plants (Basel)
Fang Y, Liu F, Wang T, Fang L, Guo J, Su S, Chen X, Zhuang L, Sun J, Ye D, Wang Z, Wang X.   +11 more
europepmc   +1 more source

Automatic Speaker Recognition System Based on Gaussian Mixture Models, Cepstral Analysis, and Genetic Selection of Distinctive Features. [PDF]

Sensors (Basel), 2022
Kamiński KA, Dobrowolski AP.
europepmc   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Effects of commercial genetic selection on gene expression in the developing neuroendocrine system of broilers. [PDF]

Poult Sci
Sinpru P, Diehl K, Ellestad LE, Porter TE.   +3 more
europepmc   +1 more source