Results 51 to 60 of about 1,247,014 (268)

Structure, function, and genetics of lipoprotein (a) [PDF]

Journal of Lipid Research, 2016
Lipoprotein (a) [Lp(a)] has attracted the interest of researchers and physicians due to its intriguing properties, including an intragenic multiallelic copy number variation in the LPA gene and the strong association with coronary heart disease (CHD).
Konrad Schmidt, Asma Noureen, Florian Kronenberg, Gerd Utermann   +3 more
openaire   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Analysis of Genetic Diversity and Structure of Eight Populations of Nerita yoldii along the Coast of China Based on Mitochondrial COI Gene

Animals
Nerita yoldii is a euryhaline species commonly found in the intertidal zone. To investigate the genetic diversity of 233 N. yoldii individuals from eight locations along the coast of China, we utilized the mitochondrial COI gene as a molecular marker.
Senping Jiang, Zhenhua Li, Jiji Li, Kaida Xu, Yingying Ye   +4 more
doaj   +1 more source

Lack of conspicuous sex‐biased dispersal patterns at different spatial scales in an Asian endemic goose species breeding in unpredictable steppe wetlands

Ecology and Evolution, 2020
Dispersal affects the spatial distribution and population structure of species. Dispersal is often male‐biased in mammals while female‐biased in birds, with the notable exception of the Anatidae.
Qin Zhu, Iderbat Damba, Qingshan Zhao, Kunpeng Yi, Nyambayar Batbayar, Tseveenmyadag Natsagdorj, Batmunkh Davaasuren, Xin Wang, Sonia Rozenfeld, Sachiko Moriguchi, Aibin Zhan, Lei Cao, Anthony D. Fox   +12 more
doaj   +1 more source

Absence of population structure across elevational gradients despite large phenotypic variation in mountain chickadees (Poecile gambeli) [PDF]

Royal Society Open Science, 2017
Montane habitats are characterized by predictably rapid heterogeneity along elevational gradients and are useful for investigating the consequences of environmental heterogeneity for local adaptation and population genetic structure.
Carrie L. Branch, Joshua P. Jahner, Dovid Y. Kozlovsky, Thomas L. Parchman, Vladimir V. Pravosudov   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Significant genetic differentiation between native and introduced farmed Burmese pythons and low risk of genetic introgression from escaped farmed individuals in Hainan Island

Conservation Science and Practice
The Burmese python (Python bivittatus) is one of the most endangered pythons and is commonly traded in the international pet industry. In addition to wild P.
Jiao Qing, Xiaofei Zhai, Shaopeng Yu, Feiyun Tu, Tongliang Wang, Jichao Wang   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Genetic diversity and genetic structure of Camellia flavida based on SSR markers

Guangxi Zhiwu
Camellia flavida is listed as a national Class Ⅱ protected plant distributed in southwestern Guangxi with high ornamental value. Understanding the genetic diversity and genetic structure of rare and endangered species can provide a theoretical reference ...
XIANG Yingying1,2, TANG Shaoqing1,2, LU Yongbin3*
doaj   +1 more source