Results 111 to 120 of about 1,723,083 (327)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Assessing Plant Genetic Diversity by Molecular Tools

open access: yesDiversity, 2009
This paper is an overview of the diverse, predominantly molecular techniques, used in assessing plant genetic diversity. In recent years, there has been a significant increase in the application of molecular genetic methods for assessing the conservation
Linda Mondini   +2 more
doaj   +1 more source

Genetic tools and techniques for Chlamydomonas reinhardtii [PDF]

open access: yesApplied Microbiology and Biotechnology, 2015
The development of tools has always been a major driving force for the advancement of science. Optical microscopes were the first instruments that allowed discovery and descriptive studies of the subcellular features of microorganisms. Although optical and electron microscopes remained at the forefront of microbiological research tools since their ...
openaire   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Genetic engineering and genome editing techniques in peanut plants

open access: diamond, 2021
Abraham Lamboro   +7 more
openalex   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Introducing a Parallel Genetic Algorithm for Global Optimization Problems

open access: yesAppliedMath
The topic of efficiently finding the global minimum of multidimensional functions is widely applicable to numerous problems in the modern world. Many algorithms have been proposed to address these problems, among which genetic algorithms and their ...
Vasileios Charilogis, Ioannis G. Tsoulos
doaj   +1 more source

When Darwin Met Einstein: Gravitational Lens Inversion with Genetic Algorithms

open access: yes, 2005
Gravitational lensing can magnify a distant source, revealing structural detail which is normally unresolvable. Recovering this detail through an inversion of the influence of gravitational lensing, however, requires optimisation of not only lens ...
Bailer-Jones   +12 more
core   +2 more sources

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