Results 91 to 100 of about 828,986 (313)

Molecular Genetic Techniques in Biomarker Analysis Relevant for Drugs Centrally Approved in Europe. [PDF]

Mol Diagn Ther, 2022
Huebner T, Steffens M, Scholl C.
europepmc   +1 more source

Genetic algorithm optimization for blind channel identification with higher order cumulant fitting

, 1997
—An important family of blind equalization algorithms identify a communication channel model based on fitting higher order cumulants, which poses a nonlinear optimization prob-lem.
Y. Wu, S. Mclaughlin, S. Chen, Wu, Y., Chen, S., McLaughlin, S.   +5 more
core  

Depauperate genetic variability detected in the American and European bison using genomic techniques

, 2009
A total of 929 polymorphic SNPs in EB (out of 54, 000 SNPs screened using a BovineSNP50 Illumina Genotyping BeadChip), and 1, 524 and 1, 403 polymorphic SNPs in WB and PB, respectively, were analysed.
Gregersen, V.R., Pertoldi, C., Demontis, D., Tokarska, M., Wójcik, J.M., Loeschcke, V., Coltman, D.   +6 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Integrated Management of Water, Nitrogen, and Genotype Selection for Enhanced Wheat Productivity in Moroccan Arid and Semi-Arid Regions

Agronomy
Bread wheat (Triticum aestivum L.) is essential global nutrition as it provides calories and protein. This study explored the impact of irrigation, environmental factors, nitrogen fertilization, and genotype selection on yield.
Ilham Khlila, Aziz Baidani, Oussama Hnizil, Ali Amamou   +3 more
doaj   +1 more source

Cytogenetic and Biochemical Genetic Techniques for Personalized Drug Therapy in Europe. [PDF]

Diagnostics (Basel), 2021
Huebner T, Scholl C, Steffens M.
europepmc   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Representing Space: A Hybrid Genetic Algorithm for Aesthetic Graph Layout [PDF]

, 1998
This paper describes a hybrid Genetic Algorithm (GA) that is used to improve the layout of a graph according to a number of aesthetic criteria.
Rodgers, Peter, Hobbs, M.H.W.
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Synthesized boron compounds: Neurotoxic and oxidative effects in an model of Alzheimer's disease

Science Progress
Objective Alzheimer's disease (AD) is characterized by amyloid-beta (Aβ1–42) aggregation, oxidative stress, and neuronal loss, necessitating novel therapeutic agents to mitigate these pathological hallmarks.
Sibel Bayıl, Özlem Özdemir Tozlu, Bora Karagul   +2 more
doaj   +1 more source