Results 131 to 140 of about 1,723,083 (327)

Preimplantational genetic diagnosis: an actual alternative with future implications [PDF]

open access: yesMedUNAB, 2005
Preimplantational genetic diagnosis (PGT) isa new technique, promoted as an alternative for prenatal diagnosisand eventually for the voluntary termination of pregnancy whenthe couple is willing .
Claudia Juliana Serrano Serrano
doaj  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Genetic diagnosis as a tool for personalized treatment of Duchenne muscular dystrophy [PDF]

open access: yes, 2016
Accurate definition of genetic mutations causing Duchenne muscular dystrophy (DMD) has always been relevant in order to provide genetic counseling to patients and families, and helps to establish the prognosis in the case where the distinction between ...
Bello, Luca, Pegoraro, Elena
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

THE SPECIATION IN GENETIC ALGORITHMS FOR PRESERVING POPULATION DIVERSITY AND OPTIMIZATION OF FUNCTIONS WITH SUBOPTIMAL SOLUTIONS

open access: yesЕлектроніка та інформаційні технології
Background. Genetic algorithms are used in various tasks and show advantages compared to other optimization methods, which may not always be applicable. However, there are cases when they can’t provide the best possible solution.
V. Pretsel, Roman Shuvar
doaj   +1 more source

Correction: Diet of the brown bear in Himalaya: Combining classical and molecular genetic techniques. [PDF]

open access: yesPLoS One, 2020
Nawaz MA   +5 more
europepmc   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Optimization of the fermentation process and antioxidant activity of mixed lactic acid bacteria for honeysuckle beverage

open access: yesFrontiers in Microbiology
The aim of the research was to obtain a high healthcare honeysuckle beverage with strong antioxidant activity. Honeysuckle (Lonicera japonica Thunb) was used as the raw material in this experiment.
Junjian Ran   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy