Results 91 to 100 of about 1,951,570 (332)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Machine learning models based on routine blood and biochemical test data for diagnosis of neurological diseases

Scientific Reports
Globally, nervous system diseases are the leading cause of disability-adjusted life-years and the second leading cause of mortality in the world. Traditional diagnostic methods for nervous system diseases are expensive.
Wanshan Ning, Zhicheng Wang, Ying Gu, Lindan Huang, Shuai Liu, Qun Chen, Yunyun Yang, Guolin Hong   +7 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Genetic Testing When There is a Mix of Compulsory and Voluntary Health Insurance [PDF]

Genetic insurance can deal with the negative effects of genetic testing on insurance coverage and income distribution when the insurer has access to information about test status. Hence, efficient testing is promoted.
Michael Hoel, Tor Iversen
core  

Testing for rare genetic causes of obesity: findings and experiences from a pediatric weight management program [PDF]

, 2022
Karyn J. Roberts, Adolfo J. Ariza, Kavitha Selvaraj, Maheen Quadri, Caren Mangarelli, Sarah H Neault, Erica E. Davis, Helen J. Binns   +7 more
openalex   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Genetic aspects of calving, growth, and carcass traits in beef cattle [PDF]

, 2003
The aim of this thesis was to learn more about the genetic background of calving, growth and carcass traits of beef cattle breeds in Sweden, and to assess the possibility of including calving traits and commercial carcass traits in the genetic evaluation.
Eriksson, Susanne
core  

What Are the Applications of AI in Genetic Testing?

, 2021
Raşit Dinç
openalex   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Impact of the public/private mix of health insurance on genetic testing [PDF]

Privacy of information is a central concern in the debate about genetic testing. Two types of social inefficiencies may occur when information about prevention and test status is private; genetic testing may not be done when it is socially efficient and ...
Hoel, Michael, Iversen, Tor
core