Results 91 to 100 of about 5,304,709 (301)
Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine
BMEMatLiposomes have emerged as the most clinically successful nanocarriers with good biocompatibility, low immunogenicity, and facile modification potential.
Yuchen Guo +9 more
doaj +1 more source
The Bottleneck in Genetic Testing [PDF]
Circulation Research, 2015 Progress in science is a continuum but not uniform. Occasional sparks, typically ignited by the so-called disruptive discoveries, decorate the continuum. Relevant to this editorial on advances in the genetic testing technologies, is the disruptive technology of capillary sequencing, also known as Sanger sequencing.1 It enabled the initial sequencing of
openaire +2 more sources
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Impact of the public/private mix of health insurance on genetic testing [PDF]
Privacy of information is a central concern in the debate about genetic testing. Two types of social inefficiencies may occur when information about prevention and test status is private; genetic testing may not be done when it is socially efficient and ...
Iversen, Tor, Hoel, Michael
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Automated unique input output sequence generation for conformance testing of FSMs [PDF]
, 2006 This paper describes a method for automatically generating unique input output (UIO) sequences for FSM conformance testing. UIOs are used in conformance testing to verify the end state of a transition sequence. UIO sequence generation is represented as a
Qiang, G +11 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
THE MORAL, SOCIAL, AND COMMERCIAL IMPERATIVES OF GENETIC TESTING AND SCREENING: THE AUSTRALIAN CASE
, 2006 Notes on contributors -- About this book -- I. Positioning -- Ch. 1. From destiny to freedom? On human nature and liberal eugenics in the age of genetic manipulation / Michela Betta -- Ch. 2. Diagnostic knowledge in the genetic economy and commerce /
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