Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Molecular Oncology, EarlyView.Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha +6 more
wiley +1 more source
Silver-Russell syndrome: genetic basis and molecular genetic testing
Orphanet Journal of Rare Diseases, 2010 Imprinted genes with a parent-of-origin specific expression are involved in various aspects of growth that are rooted in the prenatal period. Therefore it is predictable that many of the so far known congenital imprinting disorders (IDs) are clinically ...
Binder Gerhard +3 more
doaj +1 more source
Lower genetic diversity in the limpet Patella caerulea on urban coastal structures compared to natural rocky habitats [PDF]
Marine Biology 156 (2009) 2313, 2009 Human-made structures are increasingly found in marine coastal habitats. The aim of the present study was to explore whether urban coastal structures can affect the genetic variation of hard-bottom species. We conducted a population genetic analysis on the limpet Patella caerulea sampled in both natural and artificial habitats along the Adriatic coast.
arxiv
Don\u27t Try This at Home: The FDA\u27s Restrictive Regulation of Home-Testing Devices [PDF]
, 2017 Over the past forty years, the Food and Drug Administration (FDA) has successfully restricted consumers\u27 access to home-testing applications based on the notion that it should protect individuals from their own reactions to test results. In the 1970s,
Shelby Baird
core +1 more source
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini +11 more
wiley +1 more source
ASCERTAINING GENETIC CARRIERS OF HEREDITARY SPHEROCYTOSIS BY STATISTICAL ANALYSIS OF MULTIPLE LABORATORY TESTS* [PDF]
, 1962 A. A. MacKinney +3 more
openalex +1 more source
Genetic Testing When There is a Mix of Compulsory and Voluntary Health Insurance [PDF]
Genetic insurance can deal with the negative effects of genetic testing on insurance coverage and income distribution when the insurer has access to information about test status. Hence, efficient testing is promoted.
Michael Hoel, Tor Iversen
core
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Molecular Oncology, EarlyView.Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi +6 more
wiley +1 more source
Knowledge, Beliefs, and Attitudes Concerning Genetic Testing Among Young Jordanians
Journal of Multidisciplinary Healthcare, 2019 Zaid Altaany,1 Omar F Khabour,2 Ghaith Al-Taani3 1Department of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan; 2Department of Medical Laboratory Sciences, Jordan University of Science and Technology, Irbid, Jordan ...
Altaany Z, Khabour OF, Al-Taani G
doaj
Modeling and Testing for Joint Association Using a Genetic Random Field Model [PDF]
arXiv, 2013 Substantial progress has been made in identifying single genetic variants predisposing to common complex diseases. Nonetheless, the genetic etiology of human diseases remains largely unknown. Human complex diseases are likely influenced by the joint effect of a large number of genetic variants instead of a single variant. The joint analysis of multiple
arxiv