Results 131 to 140 of about 17,080,653 (424)
The Prostate, 2018 Genetic testing capability and guidelines are rapidly expanding to assess inherited prostate cancer (PCA). Clinical genetic data from multigene testing can provide insights into the germline pathogenic variant (PV) spectrum and correlates in men with PCA
V. Giri +7 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen +13 more
wiley +1 more source
Continuous salt stress-induced long non-coding RNAs and DNA methylation patterns in soybean roots
BMC Genomics, 2019 Background Environmental stimuli can activate a series of physiological and biochemical responses in plants accompanied by extensive transcriptional reprogramming.
Rui Chen +7 more
doaj +1 more source
Attitudes Toward Breast Cancer Genetic Testing in Five Special Population Groups
, 2015 Purpose: This study examined interest in and attitudes toward genetic testing in 5 different population groups. Methods: The survey included African American, Asian American, Latina, Native American, and Appalachian women with varying familial histories ...
Burhansstipanov, Linda +9 more
core
Ethical qualms about genetic prognosis [PDF]
, 2016 The debate about direct-to-consumer genetic testing has centred on whether consumers are the best judges of their own clinical care. Inthis article, I also examine whether the science of personalized medicine is really as advanced as its proponents
Dickenson, Donna
core +1 more source
Demographic differences in the utilization of clinical and direct-to-consumer genetic testing.
Journal of Genetic Counseling, 2019 Genetic testing has increased over the last decade due to growth in the number of clinical and direct-to-consumer (DTC) tests. However, there is uncertainty about how increased DTC genetic testing affects disparities.
Nikki M. Carroll +10 more
semanticscholar +1 more source
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Molecular Oncology, EarlyView.Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha +6 more
wiley +1 more source
Frontiers in GeneticsSex discordance between cell-free DNA (cfDNA) testing and ultrasound examination is rare but can cause significant patient discomfort and uncertainty.
Nuria Balaguer +6 more
doaj +1 more source
Searching for invariants using genetic programming and mutation testing [PDF]
, 2011 Invariants are concise and useful descriptions of a program's behaviour. As most programs are not annotated with invariants, previous research has attempted to automatically generate them from source code.
Clark, J.A., Ratcliff, S., White, D.R.
core +1 more source
On the valuation of genetic tests [PDF]
Personalized Medicine, 2004 10.1517/17410541.1.1.125 © 2 Continuing progress in the field of human genetics may lead to more widespread use of genetic screening in medicine. While hundreds of publications have so far reported the identification of novel genetic disease risk factors and genetic mediators of treatment response, only a few FDA-approved genetic tests are presently ...
openaire +3 more sources