Results 11 to 20 of about 912,080 (293)

Mesenchymal Stem Cell-Derived Exosomes Ameliorate Alzheimer’s Disease Pathology and Improve Cognitive Deficits

open access: yesBiomedicines, 2021
The accumulation of extracellular β-amyloid (Aβ) plaques within the brain is unique to Alzheimer’s disease (AD) and thought to induce synaptic deficits and neuronal loss. Optimal therapies should tackle the core AD pathophysiology and prevent the decline
Yi-An Chen   +7 more
doaj   +1 more source

Genetic Testing and Genetic Screening [PDF]

open access: yesKennedy Institute of Ethics Journal, 1993
In recent years there has been an enormous expansion in the knowledge that may be gleaned from the testing of an individual's genetic material to predict present or future disability or disease either for oneself or one's offspring. The Human Genome Project, which is currently mapping the entire human gene system, is identifying progressively more ...
openaire   +2 more sources

A signal-enhanced lateral flow strip biosensor for ultrasensitive and on-site detection of bisphenol A

open access: yesFood and Agricultural Immunology, 2018
A signal-enhanced lateral flow strip biosensor has been constructed for ultrasensitive and on-site visual detection of bisphenol A (BPA). The signal amplification principle is based on the capacity of binding a large number of antibody-assembled gold ...
Xiayu Peng   +6 more
doaj   +1 more source

Evidence‐based consensus guidelines for ALS genetic testing and counseling

open access: yesAnnals of Clinical and Translational Neurology, 2023
Objective Advances in amyotrophic lateral sclerosis (ALS) gene discovery, ongoing gene therapy trials, and patient demand have driven increased use of ALS genetic testing. Despite this progress, the offer of genetic testing to persons with ALS is not yet
Jennifer Roggenbuck   +5 more
doaj   +1 more source

The MyoD1 Promoted Muscle Differentiation and Generation by Activating CCND2 in Guanling Cattle

open access: yesAnimals, 2022
The purpose of this study was to analyze the transcriptome of MyoD1 gene knockout MDBK cells (bovine kidney cells) using high-throughput sequencing.
Di Zhou   +10 more
doaj   +1 more source

Cardiovascular safety of Janus kinase inhibitors in patients with rheumatoid arthritis: systematic review and network meta-analysis

open access: yesFrontiers in Pharmacology, 2023
Background: Janus kinase (JAK) inhibitors have emerged as a progressively utilized therapeutic approach for the management of rheumatoid arthritis (RA). However, the complete determination of their cardiovascular safety remains inconclusive.
Qige Wei   +21 more
doaj   +1 more source

Evaluation of a two-test strategy for HIV screening in a low-prevalence setting and the indications for optimizing clinical management

open access: yesHeliyon, 2023
Objectives: To evaluate a two-test strategy for HIV screening in the low-prevalence population and to assess the feasibility of utilizing the optimal signal-to-cutoff (S/CO) threshold on the chemiluminescence immunoassay(CMIA) and an additional rapid ...
Yu Huang   +8 more
doaj   +1 more source

Identification of Pathogenic Fusarium spp. Causing Maize Ear Rot and Poten tial Mycotoxin Production in China

open access: yesToxins, 2016
Ear rot is a serious disease that affects maize yield and grain quality worldwide. The mycotoxins are often hazardous to humans and livestock. In samples collected in China between 2009 and 2014, Fusarium verticillioides and F.
Canxing Duan   +6 more
doaj   +1 more source

Direct-to-consumer genetic testing [PDF]

open access: yesGenomics & Informatics, 2019
Direct-to-consumer (DTC) genetic testing is a controversial issue although Korean Government is considering to expand DTC genetic testing. Preventing the exaggeration and abusing of DTC genetic testing is an important task considering the early history ...
Jong-Won Kim
doaj   +1 more source

Genetic Testing Oversight [PDF]

open access: yesScience, 2006
![Figure][1] A major impact of sequencing the human genome has been the ability to detect disease and the risk of disease through genetic testing. Today, there are genetic tests for more than 1000 diseases, and that number is increasing rapidly. Given the potential powerful health consequences of genetic test results, shouldn't someone be in charge ...
openaire   +2 more sources

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