Results 21 to 30 of about 1,937,571 (305)
The MyoD1 Promoted Muscle Differentiation and Generation by Activating CCND2 in Guanling Cattle
Animals, 2022 The purpose of this study was to analyze the transcriptome of MyoD1 gene knockout MDBK cells (bovine kidney cells) using high-throughput sequencing.
Di Zhou +10 more
doaj +1 more source
Evidence‐based consensus guidelines for ALS genetic testing and counseling
Annals of Clinical and Translational Neurology, 2023 Objective Advances in amyotrophic lateral sclerosis (ALS) gene discovery, ongoing gene therapy trials, and patient demand have driven increased use of ALS genetic testing. Despite this progress, the offer of genetic testing to persons with ALS is not yet
Jennifer Roggenbuck +5 more
doaj +1 more source
Frontiers in Pharmacology, 2023 Background: Janus kinase (JAK) inhibitors have emerged as a progressively utilized therapeutic approach for the management of rheumatoid arthritis (RA). However, the complete determination of their cardiovascular safety remains inconclusive.
Qige Wei +21 more
doaj +1 more source
The withdrawal from oncogenetic counselling and testing for hereditary and familial breast and ovarian cancer. A descriptive study of an Italian sample [PDF]
, 2008 Background. Oncogenetic counselling is seldom followed through, even when individuals are eligible according to the test criteria. The basic variables which influence the decision to undergo the genetic counselling process are: risk perception, expected ...
Anita Caruso +36 more
core +2 more sources
Genetic Testing and Genetic Screening [PDF]
Kennedy Institute of Ethics Journal, 1993 In recent years there has been an enormous expansion in the knowledge that may be gleaned from the testing of an individual's genetic material to predict present or future disability or disease either for oneself or one's offspring. The Human Genome Project, which is currently mapping the entire human gene system, is identifying progressively more ...
openaire +2 more sources
Implications of avoiding overlap between training and testing data sets when evaluating genomic predictions of genetic merit [PDF]
, 2010 The aim of this study was to evaluate and quantify the importance of avoiding overlap between training and testing subsets of data when evaluating the effectiveness of predictions of genetic merit based on genetic markers.
Amer, P. R., Banos, G.
core +1 more source
Heliyon, 2023 Objectives: To evaluate a two-test strategy for HIV screening in the low-prevalence population and to assess the feasibility of utilizing the optimal signal-to-cutoff (S/CO) threshold on the chemiluminescence immunoassay(CMIA) and an additional rapid ...
Yu Huang +8 more
doaj +1 more source
Outcomes of Genetic Testing in a Genitourinary Genetics Clinic [PDF]
, 2018 Several known hereditary cancer syndromes confer an increased risk for genitourinary (GU)related malignancies. Various guidelines indicate when to refer patients to genetic counseling for GU-related hereditary cancer syndromes but there is limited ...
Pace, Annelise
core +1 more source
Context, ethics and pharmacogenetics [PDF]
, 2006 Most of the literature on pharmacogenetics assumes that the main problems in implementing the technology will be institutional ones (due to funding or regulation) and that although it involves genetic testing, the ethical issues involved in ...
Adam M. Hedgecoe +58 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source