Results 201 to 210 of about 1,824,368 (348)
GIG response to the UK Clinical Genetics Society report "The genetic testing of children". [PDF]
Simon Dalby
openalex +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
Non-Invasive Preimplantation Genetic Testing. [PDF]
Bakalova DN+2 more
europepmc +1 more source
Chinese Geneticists' Views of Ethical Issues in Genetic Testing and Screening: Evidence for Eugenics in China [PDF]
Xin Mao
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Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source
The centromere as a target for the induction of chromosome damage in resting and proliferating mammalian cells: assessment of mitomycin C-induced genetic damage at kinetochores and centromeres by a micronucleus test in mouse splenocytes [PDF]
Luigina Renzi+2 more
openalex +1 more source
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
Systematic Review: The Psychosocial Impacts of Autism-Related Genetic Testing. [PDF]
Wills BC+5 more
europepmc +1 more source