Results 211 to 220 of about 1,948,626 (333)

Insurance issues and genetic testing [PDF]

, 1997
Robert J. Pokorski, Patricia Sanderson, Nancy M. Bennett, Mary E. Costanza, Arnold A. Dicke, Harmon J. Eyre, Phyllis Hall, Shawn Hausman, Jane Lynch, Roberta B. Meyer, Stephen Sener, Richard C. Wender, Kathleen Zeitz   +12 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Unique perspectives about men's awareness of BRCA1/2 genetic testing in primary care. [PDF]

Sci Rep
Andrews CS, Ibrahim I, Baruch YB, Zisk-Rony RY, Noble A.   +4 more
europepmc   +1 more source

Genetic analysis of milk production traits of Tunisian Holsteins using random regression test-day model with Legendre polynomials [PDF]

, 2017
Hafedh Ben Zaabza, Abderrahmen Ben Gara, B. Rekik   +2 more
openalex   +1 more source

Ethical, Legal, and Social Issues in Genetic Testing for Complex Genetic Diseases [PDF]

, 2011
Andrews, Lori, Zuiker, Erin Shaugnessy
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Retraction: Genetic Testing for Successful Cancer Treatment. [PDF]

Cureus
Singh DN, Daripelli S, Elamin Bushara MO, Polevoy GG, Prasanna M.   +4 more
europepmc   +1 more source

Genetic and non-genetic factors affecting monthly test day milk yields and first lactation milk yield in crossbred cattle of Kerala [PDF]

, 2019
Gnana Prakash, K. Anilkumar, Jamuna Valsalan   +2 more
openalex  

Genetic testing [PDF]

Annals of Molecular and Genetic Medicine, 2019
openaire   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source