Results 231 to 240 of about 1,824,368 (348)

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Yield of Genetic Testing in Pediatric Cardiomyopathies: Implications for Novel Therapeutic Options. [PDF]

Mol Genet Genomic Med
Ballerini A, Girolami F, Gozzini A, Passantino S, Zampieri M, Marchi A, Tomberli A, Calabri GB, Spaziani G, Porcedda G, Bennati E, Favilli S, Olivotto I.   +12 more
europepmc   +1 more source

Social Implications of Genetic Testing

, 1999
Karen H. Rothenberg
openalex   +2 more sources

Benefits and dangers of genetic tests [PDF]

, 1998
Harry Ostrer
openalex   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Evaluating first-line genetic testing strategies for inpatients with congenital heart defects. [PDF]

J Genet Couns
Lindstrom A, Breman A, Fitzgerald-Butt S, Helvaty LR, Ware SM, Helm BM.   +5 more
europepmc   +1 more source

Clinical implications of BRCA1 genetic testing [PDF]

, 1998
Anne Dørum, Ketil Heimdal, Pål Møller
openalex   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Germline Genetic Testing in Patients With Solid Malignant Tumors.

JAMA Netw Open
Fine ME, Estrin A, Michel A, Ro V, Jones T, Trivedi MS, Crew KD.   +6 more
europepmc   +1 more source

Hypermobile Ehlers-Danlos Syndrome: Diagnostic Challenges and the Role of Genetic Testing. [PDF]

Genes (Basel)
Forghani I, See J, McGonigle WC.
europepmc   +1 more source