Results 231 to 240 of about 1,972,073 (332)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Genetic Counselling and Testing for Hereditary Breast and Ovarian Cancer: The Gent(le) Approach [PDF]

, 1999
Michel De Vos, Bruce Poppe, Immle Delvaux, Geert Mortier, Kathleen Claes, Ludwine Messiaen, Anne De Paepe   +6 more
openalex   +1 more source

Genetic Testing: practical dos and don'ts for cats. [PDF]

J Feline Med Surg
Lyons LA.
europepmc   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Are We Failing in Molecular Genetic Testing? [PDF]

, 1999
Robert A. Robinson
openalex   +1 more source

Application of Genetic Testing for Anorexia Nervosa: An Ethical Analysis. [PDF]

Brain Behav
Ramsay S, Allison K, Temples HS, Sarasua S, Boccuto L.   +4 more
europepmc   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Monitoring Impact of a Pesticide Treatment on Bacterial Soil Communities by Metabolic and Genetic Fingerprinting in Addition to Conventional Testing Procedures

, 1998
Bert Engelen, Kristin Meinken, Friedrich von Wintzingerode, Holger Heuer, Hans‐Peter Malkomes, Horst Backhaus   +5 more
openalex   +1 more source

Genetic testing for colon cancer susceptibility: Anticipated reactions of patients and challenges to providers [PDF]

, 1996
Caryn Lerman, John C. Marshall, Janet Audrain, Andres Gomez‐Caminero   +3 more
openalex   +1 more source

Deciding on genetic testing for familial dementia: Perspectives of patients and families. [PDF]

Alzheimers Dement
van der Schaar J, van der Lee SJ, Asscher ECA, Pijnenburg YAL, de Geus CM, Bredenoord AL, van der Flier WM, van den Hoven MA, Smets EMA, Visser LNC.   +9 more
europepmc   +1 more source