Clinical application of high throughput molecular screening techniques for pharmacogenomics. [PDF]
, 2011 Genetic analysis is one of the fastest-growing areas of clinical diagnostics. Fortunately, as our knowledge of clinically relevant genetic variants rapidly expands, so does our ability to detect these variants in patient samples.
Schrijver, Iris, Wiita, Arun P
core +1 more source
Food and Agricultural Immunology, 2018 A signal-enhanced lateral flow strip biosensor has been constructed for ultrasensitive and on-site visual detection of bisphenol A (BPA). The signal amplification principle is based on the capacity of binding a large number of antibody-assembled gold ...
Xiayu Peng +6 more
doaj +1 more source
Testing the Children: Do Non-Genetic Health-Care Providers Differ in Their Decision to Advise Genetic Presymptomatic Testing on Minors? A Cross-Sectional Study in Five Countries in the European Union [PDF]
, 2009 BACKGROUND: Within Europe many guidelines exist regarding the genetic testing of minors. Predictive and presymptomatic genetic testing of minors is recommended for disorders for which medical intervention/preventive measures exist, and for which early ...
Anne Marie C. Plass +15 more
core +1 more source
Comparison Study for Clonal Selection Algorithm and Genetic Algorithm [PDF]
International Journal of Computer Science & Information Technology
(IJCSIT) Vol 4, No 4, August 2012 pp 107-118, 2012 Two metaheuristic algorithms namely Artificial Immune Systems (AIS) and Genetic Algorithms are classified as computational systems inspired by theoretical immunology and genetics mechanisms. In this work we examine the comparative performances of two algorithms.
arxiv +1 more source
Direct-to-consumer genetic testing [PDF]
Genomics & Informatics, 2019 Direct-to-consumer (DTC) genetic testing is a controversial issue although Korean Government is considering to expand DTC genetic testing. Preventing the exaggeration and abusing of DTC genetic testing is an important task considering the early history ...
Jong-Won Kim
doaj +1 more source
Genetic load makes cancer cells more sensitive to common drugs: evidence from Cancer Cell Line Encyclopedia [PDF]
Scientific Reports (7:1938). Springer Nature. May 16 2017, 2017 Genetic alterations initiate tumors and enable the evolution of drug resistance. The pro-cancer view of mutations is however incomplete, and several studies show that mutational load can reduce tumor fitness. Given its negative effect, genetic load should make tumors more sensitive to anticancer drugs.
arxiv +1 more source
Genetic algorithm formulation and tuning with use of test functions [PDF]
arXiv, 2022 This work discusses single-objective constrained genetic algorithm with floating-point, integer, binary and permutation representation. Floating-point genetic algorithm tuning with use of test functions is done and leads to a parameterization with comparatively outstanding performance.
arxiv
Toxins, 2016 Ear rot is a serious disease that affects maize yield and grain quality worldwide. The mycotoxins are often hazardous to humans and livestock. In samples collected in China between 2009 and 2014, Fusarium verticillioides and F.
Canxing Duan +6 more
doaj +1 more source
Cardiac manifestations of PRKAG2 mutation. [PDF]
, 2018 BACKGROUND:The Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 2 (PRKAG2) cardiac syndrome is characterized by glycogen accumulation in the cardiac tissue.
Ardehali, Reza +3 more
core +1 more source
Robust Methods for Disease-Genotype Association in Genetic Association Studies: Calculate P-values Using Exact Conditional Enumeration instead of Asymptotic Approximations [PDF]
, 2013 In genetic association studies, detecting disease-genotype associations is a primary goal. For most diseases, the underlying genetic model is unknown, and we study seven robust test statistics for monotone association. For a given test statistic, there are many ways to calculate a p-value, but in genetic association studies, calculations have ...
arxiv +1 more source