Results 41 to 50 of about 17,080,653 (424)
Direct-to-consumer genetic testing [PDF]
Genomics & Informatics, 2019 Direct-to-consumer (DTC) genetic testing is a controversial issue although Korean Government is considering to expand DTC genetic testing. Preventing the exaggeration and abusing of DTC genetic testing is an important task considering the early history ...
Jong-Won Kim
doaj +1 more source
Comparison Study for Clonal Selection Algorithm and Genetic Algorithm [PDF]
International Journal of Computer Science & Information Technology
(IJCSIT) Vol 4, No 4, August 2012 pp 107-118, 2012 Two metaheuristic algorithms namely Artificial Immune Systems (AIS) and Genetic Algorithms are classified as computational systems inspired by theoretical immunology and genetics mechanisms. In this work we examine the comparative performances of two algorithms.
arxiv +1 more source
Clinical application of high throughput molecular screening techniques for pharmacogenomics. [PDF]
, 2011 Genetic analysis is one of the fastest-growing areas of clinical diagnostics. Fortunately, as our knowledge of clinically relevant genetic variants rapidly expands, so does our ability to detect these variants in patient samples.
Schrijver, Iris, Wiita, Arun P
core +1 more source
Journal of the American Medical Association (JAMA), 2019 Importance Potentially harmful mutations of the breast cancer susceptibility 1 and 2 genes (BRCA1/2) are associated with increased risk for breast, ovarian, fallopian tube, and peritoneal cancer.
D. Owens +15 more
semanticscholar +1 more source
Genetic load makes cancer cells more sensitive to common drugs: evidence from Cancer Cell Line Encyclopedia [PDF]
Scientific Reports (7:1938). Springer Nature. May 16 2017, 2017 Genetic alterations initiate tumors and enable the evolution of drug resistance. The pro-cancer view of mutations is however incomplete, and several studies show that mutational load can reduce tumor fitness. Given its negative effect, genetic load should make tumors more sensitive to anticancer drugs.
arxiv +1 more source
Toxins, 2016 Ear rot is a serious disease that affects maize yield and grain quality worldwide. The mycotoxins are often hazardous to humans and livestock. In samples collected in China between 2009 and 2014, Fusarium verticillioides and F.
Canxing Duan +6 more
doaj +1 more source
Genetic algorithm formulation and tuning with use of test functions [PDF]
arXiv, 2022 This work discusses single-objective constrained genetic algorithm with floating-point, integer, binary and permutation representation. Floating-point genetic algorithm tuning with use of test functions is done and leads to a parameterization with comparatively outstanding performance.
arxiv
Implications of Genetic Testing in Dilated Cardiomyopathy
Circulation Genomic and Precision Medicine, 2020 Supplemental Digital Content is available in the text. Background: Genetic analysis is a first-tier test in dilated cardiomyopathy (DCM). Electrical phenotypes are common in genetic DCM, but their exact contribution to the clinical course and outcome is ...
J. Verdonschot +11 more
semanticscholar +1 more source
Childhood genetic testing for familial cancer: should adoption make a difference? [PDF]
, 2010 Professional guidelines and practice in clinical genetics generally counsel against predictive genetic testing in childhood. A genetic test should not be performed in a child who is too young to choose it for himself unless that test is diagnostic ...
Leonard, S. J., Newson, A.J.
core +1 more source
BMC Cancer, 2022 Background In international guidelines, germline genetic testing is recommended for patients with metastatic prostate cancer. Before undergoing germline genetic testing, these patients should receive pre-test counseling.
Michiel Vlaming +4 more
doaj +1 more source