Results 121 to 130 of about 1,532,404 (358)

Correction: Systematic review and meta-analysis determining the benefits of in vivo genetic therapy in spinal muscular atrophy rodent models. [PDF]

Gene Ther, 2023
Chilcott EM, Muiruri EW, Hirst TC, Yáñez-Muñoz RJ.   +3 more
europepmc   +1 more source

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

FEBS Letters, EarlyView.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Genetic Therapy for Intervertebral Disc Degeneration. [PDF]

Int J Mol Sci, 2021
Roh EJ, Darai A, Kyung JW, Choi H, Kwon SY, Bhujel B, Kim KT, Han I.   +7 more
europepmc   +1 more source

Steady-state plasma levels of nortriptyline in twins: Influence of genetic factors and drug therapy [PDF]

, 1969
B. Alexanderson, David A. Evans, Folke Sjöqvist   +2 more
openalex   +1 more source

Human Rights Questions: From Bioethics to Biolaw [PDF]

Bioethics as a pluridisciplinary activity aims to clarify and solve actual ethical problems generated by science and bio-medical technologies. The gap between the scientific and medical progress and the law generally and Human Rights especially does not ...
Aurora CIUCA
core   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Use of low-power He-Ne laser therapy to accelerate regeneration processes of injured sciatic nerve in rabbit

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2019
Background Photostimulation using low-power laser had been used for nervous repair with interesting results. This study aimed to evaluate the influence of 20 mW low-power He-Ne laser on the regeneration of a peripheral sciatic nerve after trauma using ...
Ahmed Majeed Al-Shammari, Yahya Syhood, Ahmed S. Al-Khafaji   +2 more
doaj   +1 more source

With newer tools for gene editing, is it time to revisit genetic therapy for cystic fibrosis? [PDF]

Genes Dis, 2021
Gupta A, Gupta A, Boyd L.
europepmc   +1 more source

Gene therapy for carcinoma of the breast: Therapeutic genetic correction strategies [PDF]

, 1999
Patrice S. Obermiller, David L. Tait, Jeffrey T. Holt   +2 more
openalex   +1 more source