Results 241 to 250 of about 7,770,494 (359)

Neonatal hypophosphatasia: a case report of a rare genetic disorder. [PDF]

BMC Pediatr
Vohra WI, Chohan N, Mirza A.
europepmc   +1 more source

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

Nature, 2009
D. Ge, J. Fellay, A. Thompson, J. Simon, K. Shianna, T. Urban, E. Heinzen, P. Qiu, A. Bertelsen, A. Muir, M. Sulkowski, J. Mchutchison, D. Goldstein   +12 more
semanticscholar   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Antibody-Positive Type 1 Diabetes in a Family With a Pathogenic <i>HNF1A</i>-MODY Variant and Variable Age of Onset. [PDF]

JCEM Case Rep
McCullough ME, Dye AM, Kandasamy B, Greeley SAW, Naylor RN, Philipson LH.   +5 more
europepmc   +1 more source

Gene therapy comes of age

Science, 2018
C. Dunbar, K. High, J. Joung, D. Kohn, K. Ozawa, M. Sadelain   +5 more
semanticscholar   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Vunakizumab for Treatment of Acrodermatitis Continua of Hallopeau: A Case Report and Literature Review. [PDF]

Psoriasis (Auckl)
Yao Y, Ma Y, Zhong H, Guo F, Zhu J, Wu Y, Tang S.   +6 more
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Diabetes mellitus <i>HNF4A</i>-MODY in children from the Russian population: clinical and genetic features. [PDF]

Front Endocrinol (Lausanne)
Sechko EA, Laptev DN, Koltakova MP, Khusainova RI, Minniakhmetov IR, Kuraeva TL, Eremina IA, Titovich EV, Bezlepkina OB, Peterkova VA.   +9 more
europepmc   +1 more source