Results 241 to 250 of about 1,463,301 (359)

2023 European Society of Cardiology guidelines on the management of cardiomyopathies : Statement of endorsement by the NVVC. [PDF]

Neth Heart J
Groeneweg JA, van Dalen BM, Cox MPGJ, Heymans S, Braam RL, Michels M, Asselbergs FW.   +6 more
europepmc   +1 more source

40. Combined Immunotherapy and Anti-Angiogenic Therapy of Cancer Delivered by Genetically Engineered Non-Autologous Microencapsulated Cells [PDF]

, 2003

openalex   +1 more source

Germline variants in CDKN2A wild‐type melanoma prone families

Molecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen, Marie Loeng, Amalie Lund Holth, Per E. Lønning, Jürgen Geisler, Stian Knappskog   +5 more
wiley   +1 more source

From genetic variants to therapeutic targets: insights into understanding rheumatoid arthritis. [PDF]

Front Immunol
Chen L, Zhao J, Meng Q.
europepmc   +1 more source

Genetic variants of coagulation factor XIII, postmenopausal estrogen therapy, and risk of nonfatal myocardial infarction

, 2002
Alexander P. Reiner, Susan R. Heckbert, Hans L. Vos, Robert A. S. Ariëns, Rozenn N. Lemaître, Nicholas L. Smith, Thomas Lumley, Thomas D. Rea, Lucia A. Hindorff, Gina D. Schellenbaum, Frits R. Rosendaal, David S. Siscovick, Bruce M. Psaty   +12 more
openalex   +1 more source

698. Gene Therapy of Murine GM1 Gangliosidosis by Genetically Modified Bone Marrow Hematopoietic Progenitor Cells [PDF]

, 2004
Renata Sano, Alessandra Tessitore, Angela Ingrassia, Alessandra d’Azzo   +3 more
openalex   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Editorial: Deciphering the role of signature genes in cancer prognosis and therapy resistance. [PDF]

Front Oncol
Zanette DL, Pandey MK, Siddiqui JA.
europepmc   +1 more source

Liver tissue engineering at extrahepatic sites in mice as a potential new therapy for genetic liver diseases [PDF]

, 2005
Kazuo Ohashi, Jacob M. Waugh, Michael D. Dake, Takashi Yokoyama, Hiroyuki Kuge, Yoshiyuki Nakajima, Masaki Yamanouchi, Hiroyuki Naka, Akira Yoshioka, Mark A. Kay   +9 more
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source