Results 41 to 50 of about 7,531,202 (384)
Graft Materials and Biologics for Spinal Interbody Fusion
Biomedicines, 2019 Spinal fusion is the most widely performed procedure in spine surgery. It is the preferred treatment for a wide variety of pathologies including degenerative disc disease, spondylolisthesis, segmental instability, and deformity.
Marissa D’Souza +5 more
doaj +1 more source
Evolutionary dynamics of imatinib-treated leukemic cells by stochastic approach [PDF]
, 2008 The evolutionary dynamics of a system of cancerous cells in a model of chronic myeloid leukemia (CML) is investigated by a statistical approach. Cancer progression is explored by applying a Monte Carlo method to simulate the stochastic behavior of cell reproduction and death in a population of blood cells which can experience genetic mutations.
arxiv +1 more source
Molecular Therapy: Nucleic Acids, 2016 Usher syndrome (USH) is the most common cause of combined deaf-blindness in man. The hearing loss can be partly compensated by providing patients with hearing aids or cochlear implants, but the loss of vision is currently untreatable.
Radulfus WN Slijkerman +15 more
doaj +1 more source
BMC Pregnancy and Childbirth, 2023 Background Prenatal invasive genetic testing is commonly recommended to pregnancies of early-onset FGR or FGR combined with a structural defect. Our study aimed to explore the genetic findings for FGR without structural malformations according to ...
Xiaoqing Wu +8 more
doaj +1 more source
Advances in cell transplantation therapy and gene therapy in Parkinson's disease
Chinese Journal of Contemporary Neurology and Neurosurgery, 2022 The role of cell transplantation therapy and gene therapy in the treatment of Parkinson's disease (PD) has attracted more and more attention. It has developed from laboratory research tools to clinical products for patients.
XU Bao⁃lei, CHAN Piu
doaj +1 more source
Genetic Predictors of Response to Systemic Therapy in Esophagogastric Cancer.
Cancer Discovery, 2018 The incidence of esophagogastric cancer is rapidly rising, but only a minority of patients derive durable benefit from current therapies. Chemotherapy as well as anti-HER2 and PD-1 antibodies are standard treatments.
Y. Janjigian +39 more
semanticscholar +1 more source
Circulation, 2019 Supplemental Digital Content is available in the text. Background: The ability of a genetic risk score to predict risk in established cardiovascular disease and identify individuals who derive greater benefit from PCSK9 (proprotein convertase subtilisin ...
N. Marston +14 more
semanticscholar +1 more source
Optimization of pencil beam scanning pattern for FLASH proton therapy [PDF]
arXiv, 2023 Purpose: The FLASH effect, which reduces the radiosensitivity of healthy tissue while maintaining tumor control at high dose rates, has shown potential for improving radiation therapy. Conformal FLASH proton therapy involves advanced beam-shaping technologies and specialized nozzle designs to confine the dose to the target volume.
arxiv
Interaction of hydrogen peroxide molecules with non-specific DNA recognition sites [PDF]
, 2020 Ion beam therapy is one of the most progressive methods in cancer treatment. Studies of the water radiolysis process show that the most long-living species that occur in the medium of a biological cell under the action of ionizing irradiation are hydrogen peroxide (H$_2$O$_2$) molecules.
arxiv +1 more source
Frontiers in Oncology, 2019 The introduction of targeted therapy is the biggest success in the treatment of cancer in the past few decades. However, heterogeneous cancer is characterized by diverse molecular alterations as well as multiple clinical profiles.
Jing Jin +13 more
semanticscholar +1 more source