Results 71 to 80 of about 1,008,568 (216)

Identification of a Novel MTM1 Mutation Associated with X-Linked Myotubular Myopathy: Clinical and Molecular Insights for Prenatal Diagnosis

open access: yesInternational Journal of Women's Health
Shixin Chen,1,* Bin Liang,1,* Na Lin,1 Mian Pan,2 Li Li2 1Medical Genetic Diagnosis and Therapy Center, Fujian Key Laboratory for Prenatal Diagnosis and Birth Defects, Fujian Maternity and Child Health Hospital, College of Clinical ...
Chen S, Liang B, Lin N, Pan M, Li L
doaj  

Assessing Norton and Norton's model of play therapy through a study of a three-year-old's play therapy experience [PDF]

open access: yes, 1999
Plan BThere are a variety of play therapy models in research literature that predict stages children move through during play therapy. The purpose of this study is to assess one of these stage models.
Lamon, Kelly Elizabeth Christensen
core  

Genetic engineering of mesenchymal stem cells and its application in human disease therapy. [PDF]

open access: yes, 2010
The use of stem cells for tissue regeneration and repair is advancing both at the bench and bedside. Stem cells isolated from bone marrow are currently being tested for their therapeutic potential in a variety of clinical conditions including ...
Maria Mirotsou   +7 more
core   +1 more source

Key research breakthroughs in epilepsy of 2024

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery
In 2024, the field of epilepsy has achieved a number of far-reaching advancements in basic and clinical research. These advancements cover aspects including the discovery of new targets for epilepsy surgery, the analysis of molecular pathological ...
WANG Qun, SHAO Xiao-qiu
doaj   +1 more source

Therapeutic vascularization in regenerative medicine

open access: yesStem Cells Translational Medicine, 2020
Therapeutic angiogenesis, that is, the generation of new vessels by delivery of specific factors, is required both for rapid vascularization of tissue‐engineered constructs and to treat ischemic conditions.
Roberto Gianni‐Barrera   +7 more
doaj   +1 more source

Individualization of antiretroviral therapy [PDF]

open access: yes, 2012
Antiretroviral therapy (ART) has evolved considerably over the last three decades. From the early days of monotherapy with high toxicities and pill burdens, through to larger pill burdens and more potent combination therapies, and finally, from 2005 and ...
Pavlos, R., Phillips, E.J.
core   +1 more source

Nanoparticle-mediated mRNA delivery for cancer, autoimmunity, and genetic diseases: a rapid review

open access: yesFrontiers in Drug Delivery
IntroductionMessenger RNA (mRNA) therapeutics have advanced from experimental platforms to clinical application, driven largely by the success of lipid nanoparticle (LNP)-based COVID-19 vaccines.
Okechukwu Paul-Chima Ugwu   +5 more
doaj   +1 more source

The Emerging Treatment of BCG (Bacillus Calmette-Guérin)-Unresponsive Non–Muscle-Invasive Bladder Cancer [PDF]

open access: yesJournal of Urologic Oncology
Bacillus Calmette-Guérin (BCG) remains the cornerstone in the treatment of high-risk non-muscle-invasive bladder cancer (NMIBC), effectively preventing recurrence and progression.
Jong Ho Park, Jong Jin Oh
doaj   +1 more source

Clinical Outcomes of Fetal Ventriculomegaly: A Retrospective Analysis from a Tertiary Referral Center

open access: yesInternational Journal of Women's Health
Danhua Guo,1,2 Shuqiong He,1,2 Na Lin,1,2 Yifang Dai,1,2 Ying Li,1,2 Liangpu Xu,1– 3 Xiaoqing Wu1– 4 1Department of Medical Genetic Diagnosis and Therapy Center, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics &
Guo D   +6 more
doaj  

Exploring Embryonic and Postnatal Gene Therapy Approaches for GJB2-Related Deafness: A Scoping Review

open access: yesAudiology Research
Purpose: Hearing loss (HL) is a prevalent condition significantly impairing quality of life, with genetic mutations accounting for a substantial proportion of congenital cases, notably those involving the GJB2 gene encoding connexin 26.
Valeria Caragli, Alessandro Martini
doaj   +1 more source

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