Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
A Cutter Selection Method for 2 1/2-Axis Trochoidal Milling of the Pocket Based on Optimal Skeleton
IEEE Access, 2022 The trochoidal toolpath is generated based on skeleton. However, several different skeletons can be extracted from one pocket. To improve the efficiency of trochoidal rough milling, a cutter selection method basing the optimal skeleton is proposed ...
Feiyan Han +3 more
doaj +1 more source
GemTools: A fast and efficient approach to estimating genetic ancestry [PDF]
, 2011 To uncover the genetic basis of complex disease, individuals are often measured at a large number of genetic variants (usually SNPs) across the genome. GemTools provides computationally efficient tools for modeling genetic ancestry based on SNP genotypes.
Devlin, Bernie +4 more
core
Evaluating genetic traceability methods for captive bred marine fish and their applications in fisheries management and wildlife forensics [PDF]
, 2014 Growing demands for marine fish products is leading to increased pressure on already depleted wild populations and a rise in the aquaculture production.
Bargelloni, Luca +16 more
core +7 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Resilient seed systems for climate change adaptation and sustainable livelihoods in the East Africa sub-region: Report of training workshop, Addis Ababa Ethiopia, 17-21 September 2019 [PDF]
, 2020 Bioversity International is implementing a Dutch-supported project entitled: Resilient seed systems for climate change adaptation and sustainable livelihoods in the East Africa sub-region.
Fadda, Carlo +6 more
core
Making serine integrases work for us [PDF]
, 2017 DNA site-specific recombinases are enzymes (often associated with mobile DNA elements) that catalyse breaking and rejoining of DNA strands at specific points, thereby bringing about precise genetic rearrangements.
Stark, W. Marshall
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Genetic Sequence Matching Using D4M Big Data Approaches
, 2014 Recent technological advances in Next Generation Sequencing tools have led to increasing speeds of DNA sample collection, preparation, and sequencing. One instrument can produce over 600 Gb of genetic sequence data in a single run.
Dodson, Stephanie +2 more
core +1 more source
Spaced seeds improve k-mer-based metagenomic classification [PDF]
, 2015 Metagenomics is a powerful approach to study genetic content of environmental samples that has been strongly promoted by NGS technologies. To cope with massive data involved in modern metagenomic projects, recent tools [4, 39] rely on the analysis of k ...
Brinda, Karel +2 more
core +2 more sources