Results 81 to 90 of about 1,520,984 (293)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Haloarchaea as Promising Chassis to Green Chemistry

Microorganisms
Climate change and the scarcity of primary resources are driving the development of new, more renewable and environmentally friendly industrial processes.
Emma Bonnaud, Philippe M. Oger, Avigaël Ohayon, Yoann Louis   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Development of a Recombinase-Mediated Cassette Exchange System for Gene Knockout and Expression of Non-Native Gene Sequences in Rickettsia

Vaccines
Background/Objectives: Incidence of vector-borne diseases, including rickettsioses and anaplasmosis, has been increasing in many parts of the world. The obligate intracellular nature of rickettsial pathogens has hindered the development of robust genetic
Benjamin Cull, Nicole Y. Burkhardt, Benedict S. Khoo, Jonathan D. Oliver, Xin-Ru Wang, Lisa D. Price, Kamil Khanipov, Rong Fang, Ulrike G. Munderloh   +8 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Genetic Manipulation in Sporothrix Species: Molecular Tools, Challenges, and Applications

Journal of Fungi
Sporothrix species are thermally dimorphic fungi responsible for sporotrichosis, a globally prevalent subcutaneous mycosis and an emerging zoonotic threat, particularly in South America.
Mafalda Barros, Matheus Tavares, Ricardo Silvestre, Roberta Peres da Silva, Fernando Rodrigues   +4 more
doaj   +1 more source

Genetic tool development and systemic regulation in biosynthetic technology

Biotechnology for Biofuels, 2018
With the increased development in research, innovation, and policy interest in recent years, biosynthetic technology has developed rapidly, which combines engineering, electronics, computer science, mathematics, and other disciplines based on classical ...
Zhongxue Dai, Shangjie Zhang, Qiao Yang, Wenming Zhang, Xiujuan Qian, Weiliang Dong, Min Jiang, Fengxue Xin   +7 more
doaj   +1 more source

Pandemic (H1N1) 2009 Cluster Analysis: A Preliminary Assessment [PDF]

, 2009
Pandemic (H1N1) 2009 virus has been causing major concerns around the world because of its epidemic potential, rapid dissemination, rate of mutations, and the number of fatalities.
Alan Zulich, Charles Wick, Evan Skowronski, Michael Stanford, Patrick McCubbin, Rabih Jabbour, Samir Deshpande   +6 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source