Results 101 to 110 of about 1,520,984 (293)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Automata-based Adaptive Behavior for Economical Modelling Using Game Theory

, 2006
In this chapter, we deal with some specific domains of applications to game theory. This is one of the major class of models in the new approaches of modelling in the economic domain.
Bertelle, Cyrille, Duchamp, Gérard Henry Edmond, Ghnemat, Rawan, Oqeili, Saleh   +3 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

On the Choice of the Right Plasmid Vector(s) in the Times of Synthetic Biology

Microbial Biotechnology
Plasmid vectors are to this day the fundamental tools in molecular biology, but their selection is often guided by convenience rather than informed choice. This article revisits the architectural and functional features that determine plasmid performance
Víctor deLorenzo, Esteban Martínez‐García   +1 more
doaj   +1 more source

Effects of genomic location on ectopic integration and gene expression of a reporter gene cassette in Sulfolobus acidocaldarius

Frontiers in Microbiology
In eukaryotes and bacteria, it is well-established that the genomic location of ectopic gene integration influences the expression level due to replication-associated gene dosage effects as well as effects mediated by chromatin organization. In contrast,
Yifei Xu, Andries Ivo Peeters, Indra Bervoets, Marjan De Mey, Rani Baes, Eveline Peeters   +5 more
doaj   +1 more source

Assessing Plant Genetic Diversity by Molecular Tools

Diversity, 2009
This paper is an overview of the diverse, predominantly molecular techniques, used in assessing plant genetic diversity. In recent years, there has been a significant increase in the application of molecular genetic methods for assessing the conservation
Linda Mondini, Arshiya Noorani, Mario A. Pagnotta   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries. [PDF]

, 2020
This review summarizes the last decade of work by the ENIGMA (Enhancing NeuroImaging Genetics through Meta Analysis) Consortium, a global alliance of over 1400 scientists across 43 countries, studying the human brain in health and disease.
Adhikari, Bhim M, Agartz, Ingrid, Aghajani, Moji, Aleman, André, Althoff, Robert R, Altmann, Andre, Andreassen, Ole A, Baron, David A, Bartnik-Olson, Brenda L, Baskin-Sommers, Arielle R, Baune, Bernhard T, Bearden, Carrie E, Berner, Laura A, Bertolín, Sara, Boedhoe, Premika SW, Bralten, Janita, Bright, Joanna, Brouwer, Rachel M, Bruin, Willem B, Buitelaar, Jan K, Bülow, Robin, Caeyenberghs, Karen, Cecil, Charlotte AM, Chen, Jian, Ching, Christopher RK, Chye, Yann, Cohen, Ronald A, Cole, James H, Conrod, Patricia J, Dannlowski, Udo, De Brito, Stephane A, de Kovel, Carolien GF, de Zwarte, Sonja MC, Dennis, Emily L, Desrivieres, Sylvane, Dima, Danai, Donohoe, Gary, Ehrlich, Stefan, Esopenko, Carrie, Eyler, Lisa T, Fairchild, Graeme, Faraone, Stephen V, Favre, Pauline, Filippi, Courtney A, Fisher, Simon E, Fouche, Jean-Paul, Francks, Clyde, Frodl, Thomas, Garijo, Daniel, Gil, Yolanda, Grabe, Hans J, Grasby, Katrina L, Hajek, Tomas, Han, Laura KM, Hatton, Sean N, Hilbert, Kevin, Ho, Tiffany C, Holleran, Laurena, Homuth, Georg, Hosten, Norbert, Houenou, Josselin, Ivanov, Iliyan, Jahanshad, Neda, Jia, Tianye, Kelly, Sinead, Klein, Marieke, Kwon, Jun Soo, Laansma, Max A, Leerssen, Jeanne, Lueken, Ulrike, Marie Bas-Hoogendam, Janna, Neill, Joseph O', Nunes, Abraham, Opel, Nils, Piras, Fabrizio, Piras, Federica, Postema, Merel C, Pozzi, Elena, Salminen, Lauren E, Shatokhina, Natalia, Soriano-Mas, Carles, Spalletta, Gianfranco, Sun, Daqiang, Teumer, Alexander, Thomopoulos, Sophia I, Thompson, Paul M, Tilot, Amanda K, Tozzi, Leonardo, van der Merwe, Celia, Van Someren, Eus JW, van Wingen, Guido A, Völzke, Henry, Walton, Esther, Wang, Lei, Winkler, Anderson M, Wittfeld, Katharina, Wright, Margaret J, Yun, Je-Yeon, Zhang, Guohao, Zhang-James, Yanli   +99 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Genetic Engineering -Tool for Mankind

European Journal of Engineering and Technology Research, 2018
This study was conveyed to send a driven research of Genetic Engineering its Tools, Applications, as well as Ethics which are some of the areas of Genetic Engineering which has impact on human life. Some people think Genetic Engineering as a boon where as some people think genetic engineering are way to interrupt the natural process.
Shashwat Mandal, Christian Bach
openaire   +2 more sources