Results 121 to 130 of about 752,866 (297)
Genetic learning as an explanation of stylized facts of foreign exchange markets [PDF]
This paper revisits the Kareken-Wallace model of exchange rate formation in a two-country overlapping generations world. Following the seminal paper by Arifovic (Journal of Political Economy, 104, 1996, 510 – 541) we investigate a dynamic version of the ...
Schornstein, Sascha, Lux, Thomas
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Genetic Programming for Low-Resource Systems [PDF]
, 2009 Embedded systems dominate the computing landscape. This dominance is increasing with the advent of ubiquitous computing whereby lightweight, low-resource systems are being deployed on a vast scale.
White, David Robert
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
OPTIMIZING PROJECT TIME-COST-QUALITY BY USING GENETIC ALGORITHMS [PDF]
Project management causes the problem of efficient resource assignment, activity, time constraints and relationships between activities. Traditional scheduling methods like CPM and PERT are incomplete tools to use in practice because they do not consider
Ileana Ruxandra BADEA +1 more
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
A preliminary attempt at collecting tools and utilities for genetic data as an R package called gap is described. Genomewide association is then described as a specific example, linking the work of Risch and Merikangas (1996), Long and Langley (1997) for
Jing Hua Zhao
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Biotechnological tools for genetic improvement of Trichoderma
Scientia AgropecuariaTrichoderma is a cosmopolitan fungus widely distributed around the world. The different uses of this beneficial fungus are varied in several industries, like agriculture, textile, and paper, including the pharmaceutical industry.
Liliana Villao-Uzho +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Genetic variability of cultivated cowpea in Benin assessed by random amplified polymorphic DNA
, 2008 Characterization of genetic diversity among cultivated cowpea [Vigna unguiculata (L.) Walp.] varieties is important to optimize the use of available genetic resources by farmers, local communities, researchers and breeders.
Zannou, A. +6 more
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Applying Molecular Genetic Tools to Tiger Conservation
, 2010 The utility of molecular genetic approaches in conservation of endangered taxa is now commonly recognized. Over the past decade, conservation genetic analyses based on mitochondrial DNA sequencing and microsatellite genotyping have provided powerful ...
O\u27Brien, Stephen J. +5 more
core +1 more source